Bitam Fatma, Letizia Ciavatta M, Manzo Emiliano, Dibi Ammar, Gavagnin Margherita
Istituto di Chimica Biomolecolare, C.N.R., Naples, Italy.
Phytochemistry. 2008 Dec;69(17):2984-92. doi: 10.1016/j.phytochem.2008.09.025. Epub 2008 Nov 12.
Chemical investigation of endemic Algerian plant Launaea arborescens resulted in the isolation of a series of triterpenes and sesquiterpenes from both the aerial parts and roots. Five terpenoids have been chemically characterised by means of spectral methods mainly NMR techniques. In addition, the absolute stereochemistry at the chiral carbon in the side chain of 8-deoxy-15-(3'-hydroxy-2'-methyl-propanoyl)-lactucin-3'-sulfate (6) has been determined by comparison of the (1)H NMR spectra of Mosher derivatives of 6 with those of the corresponding MTPA esters of model compounds.
对阿尔及利亚特有植物乔木状栓果菊进行化学研究，从其地上部分和根部分离出了一系列三萜类化合物和倍半萜类化合物。借助光谱方法（主要是核磁共振技术）对五种萜类化合物进行了化学表征。此外，通过比较8-脱氧-15-（3'-羟基-2'-甲基丙酰基）-莴苣素-3'-硫酸盐（6）的莫舍尔衍生物的¹H NMR光谱与模型化合物相应的MTPA酯的光谱，确定了6侧链上手性碳的绝对立体化学结构。
