中国查获的盐酸甲基苯丙胺类毒品中杂质的鉴定及统计分类

Identification of impurities and statistical classification of methamphetamine hydrochloride drugs seized in China.

作者信息

Zhang Jian Xin, Zhang Da Ming, Han Xu Guang

机构信息

Forensic Medical Examination Center of Beijing Public Security Bureau, Beijing, China.

出版信息

Forensic Sci Int. 2008 Nov 20;182(1-3):13-9. doi: 10.1016/j.forsciint.2008.09.012. Epub 2008 Nov 12.

DOI:10.1016/j.forsciint.2008.09.012

PMID:19008060

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2615468/

Abstract

A total of 48 methamphetamine hydrochloride samples from eight seizures were analyzed using gas chromatography-mass spectrometry (GC-MS) and gas chromatography with a flame ionization detector (GC-FID). Major impurities detected include 1,2-dimethyl-3-phenylaziridine, ephedrine/pseudoephedrine, 1,3-dimethyl-2-phenylnaphthalene, 1-benzyl-3-methylnaphthalene. These data are suggestive of ephedrine/pseudoephedrine as the main precursor of the methamphetamine hydrochloride samples seized during 2006-2007. Additionally the presence of 1,3-dimethyl-2-phenylnaphthalene, 1-benzyl-3-methylnaphthalene is indicative that six seizures were synthesized via the more specific ephedrine/hydriodic acid/red phosphorus method. In addition, five impurities were found for the first time in methamphetamine hydrochloride samples. Seventeen impurity peaks were selected from the GC-FID chromatograms. The peak areas of the selected peaks were then grouped for cluster analysis.

摘要

使用气相色谱-质谱联用仪（GC-MS）和带火焰离子化检测器的气相色谱仪（GC-FID）对来自八次缉获行动的总共48个盐酸甲基苯丙胺样品进行了分析。检测到的主要杂质包括1,2-二甲基-3-苯基氮丙啶、麻黄碱/伪麻黄碱、1,3-二甲基-2-苯基萘、1-苄基-3-甲基萘。这些数据表明麻黄碱/伪麻黄碱是2006年至2007年期间缉获的盐酸甲基苯丙胺样品的主要前体。此外，1,3-二甲基-2-苯基萘、1-苄基-3-甲基萘的存在表明六次缉获的样品是通过更特定的麻黄碱/氢碘酸/红磷法合成的。此外，在盐酸甲基苯丙胺样品中首次发现了五种杂质。从GC-FID色谱图中选择了17个杂质峰。然后将所选峰的峰面积进行分组以进行聚类分析。

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