Ko Beom Jun, Suh Sungill, Suh Yong Jun, In Moon Kyo, Kim Sung-Hong
Drug Signature Analysis Center, Supreme Prosecutors' Office, Banporo, Seochogu, Seoul, Republic of Korea.
Forensic Sci Int. 2007 Aug 6;170(2-3):142-7. doi: 10.1016/j.forsciint.2007.03.029. Epub 2007 Jul 13.
Impurity profiling and classification of seized methamphetamine may play an important role in the interpretation of analytical results, the determination of the synthetic method employed, and the criminal investigations of drug traffic routes. Our study is focused on classifying seized methamphetamine samples according to the groups sorted by the types and quantities of impurities present in illicit methamphetamine samples. The samples (100mg) were dissolved in 2 mL of potassium phosphate buffer (pH 7.0), extracted with 200 microL of ethyl acetate under basic condition, and then analyzed by gas chromatography-mass spectrometry (GC-MS) with a DB-1 capillary column (30 m x 0.25 mm i.d., 0.25 microm). Five impurities are used as criteria for the classification of seized methamphetamine samples by Emde and Nagai method. A total of fifty-two samples of seized methamphetamine were analyzed by GC-MS and classified by five organic impurities, and then sorted into four groups, which are Nagai type, Emde Type, Undetermined I type, and Undetermined II type.
缴获甲基苯丙胺的杂质剖析与分类在分析结果解读、所用合成方法的确定以及毒品贩运路线的刑事调查中可能发挥重要作用。我们的研究重点是根据非法甲基苯丙胺样品中杂质的类型和数量进行分组，对缴获的甲基苯丙胺样品进行分类。将样品（100毫克）溶解于2毫升磷酸钾缓冲液（pH 7.0）中，在碱性条件下用200微升乙酸乙酯萃取，然后采用DB - 1毛细管柱（30米×0.25毫米内径，0.25微米）通过气相色谱 - 质谱联用仪（GC - MS）进行分析。采用Emde和Nagai方法，以五种杂质作为缴获甲基苯丙胺样品分类的标准。通过GC - MS对总共52份缴获的甲基苯丙胺样品进行分析，并根据五种有机杂质进行分类，然后分为四组，即Nagai型、Emde型、未确定I型和未确定II型。
