Davidson Mark G, Coutts Jonathan, Bell Graham
Royal Hospital for Sick Children, Yorkhill, Glasgow, United Kingdom.
Pediatr Pulmonol. 2008 Dec;43(12):1188-92. doi: 10.1002/ppul.20910.
To define the benefits of a flexible bronchoscopy (FB) service in a Paediatric Intensive Care Unit (PICU).
Review of the first 200 FBs undertaken in a large PICU.
Large cardiac and medical PICU in the United Kingdom, also providing extra-corporeal life support.
129 patients (78 males, 51 females, median age 9.9 months, median weight 4.6 kg) underwent FB from August 1990 to June 2003.
Broncho-alveolar lavage (BAL) as indicated at time of bronchoscopy.
Basic patient parameters were identified, including ventilation modes and diagnoses. FB findings were correlated with microbiology results.
The majority of the FBs were diagnostic (161 of 200). 114 of these were undertaken to exclude underlying airway abnormalities and 47 to aid the diagnosis of pneumonia. Therapeutic procedures including bronchial stenting, directed surfactant instillation and broncho-alveolar toileting were undertaken in 39 cases. 68% of the diagnostic FBs were deemed to be abnormal. 16% had significant extra-luminal airway obstruction. 24% had new findings of airway anomalies. 14.5% of the FBs showed endo-tracheal tube misplacement. Positive microbiological results which altered or confirmed changes in patient management occurred in 46.1% children who had BAL specimens cultured. 80 of the FBs were undertaken whilst the children were receiving extra-corporeal life support. Only one FB procedure was ceased because of patient instability.
There is a high yield of positive findings from undertaking FB both anatomically and microbiologically. FB should be seen as a routine diagnostic and therapeutic tool in paediatric intensive care.
确定小儿重症监护病房(PICU)中柔性支气管镜检查(FB)服务的益处。
回顾在一家大型PICU进行的前200例FB检查。
英国一家大型心脏和医学PICU,也提供体外生命支持。
1990年8月至2003年6月期间,129例患者(78例男性,51例女性,中位年龄9.9个月,中位体重4.6千克)接受了FB检查。
根据支气管镜检查时的指征进行支气管肺泡灌洗(BAL)。
确定基本的患者参数,包括通气模式和诊断。FB检查结果与微生物学结果相关。
大多数FB检查具有诊断意义(200例中的161例)。其中114例是为了排除潜在的气道异常,47例是为了辅助诊断肺炎。39例进行了包括支气管支架置入、定向表面活性剂滴注和支气管肺泡清理等治疗操作。68%的诊断性FB检查被认为异常。16%有明显的管腔外气道阻塞。24%有气道异常的新发现。14.5%的FB检查显示气管插管位置不当。在进行BAL标本培养的儿童中,46.1%的微生物学结果呈阳性,改变或证实了患者管理的变化。80例FB检查是在儿童接受体外生命支持时进行的。只有1例FB检查因患者不稳定而中止。
FB检查在解剖学和微生物学方面的阳性发现率很高。FB应被视为小儿重症监护中的常规诊断和治疗工具。