Berman Helen M, Westbrook John D, Gabanyi Margaret J, Tao Wendy, Shah Raship, Kouranov Andrei, Schwede Torsten, Arnold Konstantin, Kiefer Florian, Bordoli Lorenza, Kopp Jürgen, Podvinec Michael, Adams Paul D, Carter Lester G, Minor Wladek, Nair Rajesh, La Baer Joshua
Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA.
Nucleic Acids Res. 2009 Jan;37(Database issue):D365-8. doi: 10.1093/nar/gkn790. Epub 2008 Nov 14.
The Protein Structure Initiative Structural Genomics Knowledgebase (PSI SGKB, http://kb.psi-structuralgenomics.org) has been created to turn the products of the PSI structural genomics effort into knowledge that can be used by the biological research community to understand living systems and disease. This resource provides central access to structures in the Protein Data Bank (PDB), along with functional annotations, associated homology models, worldwide protein target tracking information, available protocols and the potential to obtain DNA materials for many of the targets. It also offers the ability to search all of the structural and methodological publications and the innovative technologies that were catalyzed by the PSI's high-throughput research efforts. In collaboration with the Nature Publishing Group, the PSI SGKB provides a research library, editorials about new research advances, news and an events calendar to present a broader view of structural biology and structural genomics. By making these resources freely available, the PSI SGKB serves as a bridge to connect the structural biology and the greater biomedical communities.
蛋白质结构计划结构基因组学知识库（PSI SGKB，http://kb.psi-structuralgenomics.org）的创建目的是将PSI结构基因组学工作的成果转化为可供生物学研究界用于理解生命系统和疾病的知识。该资源提供了对蛋白质数据银行（PDB）中结构的集中访问，以及功能注释、相关同源模型、全球蛋白质靶点追踪信息、可用方案，还有获取许多靶点DNA材料的可能性。它还具备搜索所有结构和方法学出版物以及由PSI高通量研究工作催生的创新技术的能力。与自然出版集团合作，PSI SGKB提供了一个研究文库、关于新研究进展的社论、新闻以及一个活动日历，以展现结构生物学和结构基因组学的更广阔图景。通过免费提供这些资源，PSI SGKB成为连接结构生物学和更广泛生物医学领域的桥梁。
