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益生菌动物双歧杆菌乳亚种AD011的基因组序列。

Genome sequence of the probiotic bacterium Bifidobacterium animalis subsp. lactis AD011.

作者信息

Kim Jihyun F, Jeong Haeyoung, Yu Dong Su, Choi Sang-Haeng, Hur Cheol-Goo, Park Myeong-Soo, Yoon Sung Ho, Kim Dae-Won, Ji Geun Eog, Park Hong-Seog, Oh Tae Kwang

机构信息

Korea Research Institute of Bioscience and Biotechnology, 111 Gwahangno, Yuseong, Daejeon 305-806, Korea.

出版信息

J Bacteriol. 2009 Jan;191(2):678-9. doi: 10.1128/JB.01515-08. Epub 2008 Nov 14.

Abstract

Bifidobacterium animalis subsp. lactis is a probiotic bacterium that naturally inhabits the guts of most mammals, including humans. Here we report the complete genome sequence of B. animalis subsp. lactis AD011 that was isolated from an infant fecal sample. Biological functions encoded in a single circular chromosome of 1,933,695 bp, smallest among the completely sequenced bifidobacterial genomes, are suggestive of their probiotic functions, such as utilization of bifidogenic factors and a variety of glycosidic enzymes and biosynthesis of polysaccharides.

摘要

动物双歧杆菌乳亚种是一种益生菌,自然存在于包括人类在内的大多数哺乳动物的肠道中。在此,我们报告了从婴儿粪便样本中分离出的动物双歧杆菌乳亚种AD011的完整基因组序列。其1,933,695 bp的单条环状染色体中编码的生物学功能,在已完成全序列测定的双歧杆菌基因组中是最小的,这表明了它们的益生菌功能,如利用双歧因子、多种糖苷酶以及多糖的生物合成。

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