乳双歧杆菌亚种。乳双歧杆菌 BB-12 的完整基因组序列，一种广泛食用的益生菌菌株。
Complete genome sequence of Bifidobacterium animalis subsp. lactis BB-12, a widely consumed probiotic strain.
机构信息
Department of Physiology, Chr Hansen A/S, Hørsholm DK-2970, Denmark.
出版信息
J Bacteriol. 2010 May;192(9):2467-8. doi: 10.1128/JB.00109-10. Epub 2010 Feb 26.
Abstract
Bifidobacterium animalis subsp. lactis BB-12 is a commercially available probiotic strain used throughout the world in a variety of functional foods and dietary supplements. The benefits of BB-12 have been documented in a number of independent clinical trials. Determination of the complete genome sequence reveals a single circular chromosome of 1,942,198 bp with 1,642 predicted protein-encoding genes, 4 rRNA operons, and 52 tRNA genes. Knowledge of this sequence will lead to insight into the specific features which give this strain its probiotic properties.
摘要
动物双歧杆菌亚种乳双歧杆菌 BB-12 是一种市售的益生菌菌株，广泛应用于各种功能性食品和膳食补充剂。BB-12 的益处已在许多独立的临床试验中得到证实。全基因组序列的测定揭示了一个单一的圆形染色体，长度为 1,942,198bp，包含 1,642 个预测的蛋白质编码基因、4 个 rRNA 操纵子和 52 个 tRNA 基因。对该序列的了解将有助于深入了解使该菌株具有益生菌特性的特定特征。
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