赛米利疱疹病毒DNA的结构与功能
Structure and function of herpesvirus saimira DNA.
作者信息
Fleckenstein B, Bornkamm G W
出版信息
IARC Sci Publ (1971). 1975(11 Pt 1):145-9.
PMID:190116
Abstract
Two types of genomes are present in HVS stocks: (1) the defective H-genome consisting of highly reiterated heavy (71% C+G) sequences; and (2) the M-genome, which carries the whole genetic information of HVS and is infectious in tissue culture. The sequences in the M-genome are made up of 70% unique L-DNA (with 36% C + G) and 30% H-DNA, which is highly repetitive. H-sequences in the M-genome are clustered at the ends of the molecule.
摘要
HVS毒株中有两种类型的基因组：（1）缺陷型H基因组，由高度重复的重链（71% C+G）序列组成；（2）M基因组，它携带HVS的全部遗传信息，且在组织培养中具有传染性。M基因组中的序列由70%的独特L-DNA（36% C + G）和30%的高度重复的H-DNA组成。M基因组中的H序列聚集在分子末端。
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