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普通狨猴(绢毛猴)对猴疱疹病毒致癌株和减毒株的易感性。

Susceptibility of common marmosets (Callithrix jacchus) to oncogenic and attenuated strains of Herpesvirus saimiri.

作者信息

Wright J, Falk L A, Wolfe L G, Ogden J, Deinhardt F

出版信息

J Natl Cancer Inst. 1977 Nov;59(5):1475-8.

PMID:198565
Abstract

Adult common marmosets, inoculated with either of 2 oncogenic Herpesvirus saimiri (HVS) strains, developed fatal lymphoproliferative disease within 23-25 days post inoculation (PI). The disease was identical to HVS-induced lymphoma in cotton-topped and white-lipped marmosets. Common marmosets inoculated with an attenuated HVS strain developed persistent infection; virus has been recovered from cocultivated lymphocytes of these animals for more than 384 days PI.

摘要

成年普通狨猴接种两种致癌性赛米利疱疹病毒(HVS)毒株中的任何一种后,在接种后23 - 25天内会发展为致命的淋巴增生性疾病。该疾病与棉顶狨猴和白唇狨猴中由HVS诱导的淋巴瘤相同。接种减毒HVS毒株的普通狨猴会发生持续性感染;在接种后超过384天,已从这些动物共培养的淋巴细胞中分离出病毒。

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