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Cancer statistics, 2008.2008年癌症统计数据。
CA Cancer J Clin. 2008 Mar-Apr;58(2):71-96. doi: 10.3322/CA.2007.0010. Epub 2008 Feb 20.
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In vivo MRI volumetric measurement of prostate regression and growth in mice.小鼠前列腺消退和生长的体内MRI体积测量
BMC Urol. 2007 Jul 24;7:12. doi: 10.1186/1471-2490-7-12.
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Magnetic resonance imaging and histopathological characterization of prostate tumors in TRAMP mice as model for pre-clinical trials.以TRAMP小鼠前列腺肿瘤作为临床前试验模型的磁共振成像和组织病理学特征
Prostate. 2007 Mar 1;67(4):396-404. doi: 10.1002/pros.20511.
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In vivo magnetic resonance volumetric and spectroscopic analysis of mouse prostate cancer models.小鼠前列腺癌模型的体内磁共振容积和光谱分析
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Suppression of prostate carcinogenesis by dietary supplementation of celecoxib in transgenic adenocarcinoma of the mouse prostate model.在小鼠前列腺转基因腺癌模型中,通过饮食补充塞来昔布抑制前列腺癌发生。
Cancer Res. 2004 May 1;64(9):3334-43. doi: 10.1158/0008-5472.can-03-2422.
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Inhibition of prostate carcinogenesis in TRAMP mice by oral infusion of green tea polyphenols.经口灌胃绿茶多酚对TRAMP小鼠前列腺癌发生的抑制作用
Proc Natl Acad Sci U S A. 2001 Aug 28;98(18):10350-5. doi: 10.1073/pnas.171326098. Epub 2001 Aug 14.
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Chemoprevention of prostate carcinogenesis by alpha-difluoromethylornithine in TRAMP mice.α-二氟甲基鸟氨酸对TRAMP小鼠前列腺癌发生的化学预防作用
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使用3特斯拉临床磁共振成像系统对小鼠前列腺进行成像。

Imaging Mouse Prostate Gland by 3 Tesla Clinical MRI System.

作者信息

Rad A M, Gao X, Deeb D, Gautam S C, Arbab A S

机构信息

Department of Radiology, Henry Ford Hospital, Detroit, Michigan.

出版信息

Open Magn Reson Rev. 2008;1:60-63. doi: 10.2174/1874769800801010060.

DOI:10.2174/1874769800801010060
PMID:19011697
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2583118/
Abstract

In vivo detection of prostate tumor in animal model will facilitate the investigations that deal with the efficacy of different treatment strategies in different experimental settings. Recently higher field strength dedicated animal MRI system has been used successfully to detect mouse prostate glands and its lesions, however, usefulness of clinical system has not been utilized to its fullest extent. In this short communication we show the advantages and disadvantages of different in vivo imaging parameters of MRI to acquire images of the mouse prostate gland using clinical strength MRI systems.

摘要

在动物模型中对前列腺肿瘤进行体内检测将有助于在不同实验环境下研究不同治疗策略的疗效。最近,更高场强的专用动物MRI系统已成功用于检测小鼠前列腺及其病变,然而,临床系统的效用尚未得到充分利用。在这篇简短的通讯中,我们展示了使用临床场强MRI系统获取小鼠前列腺图像时,MRI不同体内成像参数的优缺点。