Rad A M, Gao X, Deeb D, Gautam S C, Arbab A S
Department of Radiology, Henry Ford Hospital, Detroit, Michigan.
Open Magn Reson Rev. 2008;1:60-63. doi: 10.2174/1874769800801010060.
In vivo detection of prostate tumor in animal model will facilitate the investigations that deal with the efficacy of different treatment strategies in different experimental settings. Recently higher field strength dedicated animal MRI system has been used successfully to detect mouse prostate glands and its lesions, however, usefulness of clinical system has not been utilized to its fullest extent. In this short communication we show the advantages and disadvantages of different in vivo imaging parameters of MRI to acquire images of the mouse prostate gland using clinical strength MRI systems.
在动物模型中对前列腺肿瘤进行体内检测将有助于在不同实验环境下研究不同治疗策略的疗效。最近,更高场强的专用动物MRI系统已成功用于检测小鼠前列腺及其病变,然而,临床系统的效用尚未得到充分利用。在这篇简短的通讯中,我们展示了使用临床场强MRI系统获取小鼠前列腺图像时,MRI不同体内成像参数的优缺点。