Eum Joo-Hun David, Jeibmann Astrid, Wiesmann Werner, Paulus Werner, Ebel Heinrich
Department of Neurosurgery, University Hospital of Münster, Germany.
J Neurosurg. 2009 Apr;110(4):737-9. doi: 10.3171/2008.2.17652.
Primary intracerebral manifestation of multiple myeloma is rare and usually arises from the meninges or brain parenchyma. The authors present a case of multiple myeloma primarily manifesting within the lateral ventricle. A 67-year-old man was admitted with headache accompanied by slowly progressing right hemiparesis. Magnetic resonance imaging showed a large homogeneous contrast-enhancing intraventricular midline mass and hydrocephalus. The tumor was completely resected, and histopathological examination revealed plasmacytoma. After postoperative radio- and chemotherapy, vertebral osteolysis was detected as a secondary manifestation of multiple myeloma.
多发性骨髓瘤的原发性颅内表现罕见，通常起源于脑膜或脑实质。作者报告了一例主要表现为侧脑室内的多发性骨髓瘤病例。一名67岁男性因头痛伴右侧偏瘫缓慢进展入院。磁共振成像显示脑室内中线有一个大的均匀强化肿块及脑积水。肿瘤被完全切除，组织病理学检查显示为浆细胞瘤。术后放化疗后，检测到椎体骨质溶解为多发性骨髓瘤的继发表现。
