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空肠弯曲菌对雏鸡的实验性定植

Experimental chick colonization by Campylobacter jejuni.

作者信息

Davis Lindsay, DiRita Victor

机构信息

Department of Microbiology and Immunology, University of Michigan-Ann Arbor, Ann Arbor, Michigan, USA.

出版信息

Curr Protoc Microbiol. 2008 Nov;Chapter 8:Unit 8A.3. doi: 10.1002/9780471729259.mc08a03s11.

DOI:10.1002/9780471729259.mc08a03s11
PMID:19016444
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5147583/
Abstract

Campylobacter jejuni is commonly isolated from animals, including rodents, farm animals, and especially birds. The most common route of infection for humans is through the ingestion of contaminated chicken. Although C. jejuni commonly inhabits a number of animals, it does so asymptomatically. Many animals have been explored for use in pathogenic models; however, the most commonly used and established animal model is the chick colonization model described in this unit.

摘要

空肠弯曲菌通常可从包括啮齿动物、农场动物尤其是鸟类等动物中分离得到。人类最常见的感染途径是摄入受污染的鸡肉。尽管空肠弯曲菌通常寄生于多种动物体内,但这些动物并无症状。人们已经探索了多种动物用于致病模型;然而,最常用且成熟的动物模型是本单元所述的雏鸡定植模型。

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本文引用的文献

1
C57BL/6 and congenic interleukin-10-deficient mice can serve as models of Campylobacter jejuni colonization and enteritis.C57BL/6小鼠和同基因白细胞介素-10缺陷型小鼠可作为空肠弯曲菌定植和肠炎的模型。
Infect Immun. 2007 Mar;75(3):1099-115. doi: 10.1128/IAI.00833-06. Epub 2006 Nov 27.
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Campylobacter jejuni colonization of mice with limited enteric flora.空肠弯曲菌在肠道菌群有限的小鼠中的定殖。
Infect Immun. 2006 Sep;74(9):5261-71. doi: 10.1128/IAI.01094-05.
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Identification of Campylobacter jejuni genes involved in commensal colonization of the chick gastrointestinal tract.
空肠弯曲菌定植与无明显炎症小鼠盲肠微生物群的失调有关。
PLoS One. 2013 Sep 16;8(9):e75325. doi: 10.1371/journal.pone.0075325. eCollection 2013.
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Increase in Campylobacter jejuni invasion of intestinal epithelial cells under low-oxygen coculture conditions that reflect the in vivo environment.在低氧共培养条件下,模拟体内环境,空肠弯曲菌对肠道上皮细胞的侵袭能力增强。
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Critical role of LuxS in the virulence of Campylobacter jejuni in a guinea pig model of abortion.LuxS 在空肠弯曲菌致豚鼠流产模型中的毒力中的关键作用。
Infect Immun. 2012 Feb;80(2):585-93. doi: 10.1128/IAI.05766-11. Epub 2011 Dec 5.
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Animal models of Campylobacter jejuni colonization and disease and the lessons to be learned from similar Helicobacter pylori models.空肠弯曲菌定植与疾病的动物模型以及从类似幽门螺杆菌模型中汲取的经验教训。
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Involvement of a plasmid in virulence of Campylobacter jejuni 81-176.空肠弯曲菌81-176毒力中一种质粒的作用。
Infect Immun. 2000 Aug;68(8):4384-90. doi: 10.1128/IAI.68.8.4384-4390.2000.
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Colonization characteristics of Campylobacter jejuni in chick ceca.空肠弯曲菌在雏鸡盲肠中的定植特征
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