Mardynsky Y S, Sysoyev A S, Andreyev V G, Gulidov I A
Insitute of Medical Radiology of Academy of Medical Science, Obninsk, USSR.
Strahlenther Onkol. 1991 Mar;167(3):169-71.
Since 1985 treatment of cancer patients on BR-10 reactor has been carried out in the Institute of Medical Radiology. Till May, 1989, 78 patients have received mixed gamma-neutron therapy and combined treatment (preoperative radiation therapy and surgery). Marked late local reactions (perichondritis) were observed only in three (7%) out of 42 patients treated with radical radiation therapy alone. 43 patients had a follow-up period of two years. Among them T2 tumors were registered in six (14%) cases, T3 in 28 (65%) cases, T4 in nine (21%) cases. Regional metastases were observed in 13 (30%) patients. 19 out of 27 patients (70%) treated with radical gamma-neutron therapy and 13 out of 16 patients (81%) treated with combined therapy using reactor fast neutrons as preoperative radiation therapy are alive two years without evidence of the disease.
自1985年起，医学放射学研究所开始利用BR - 10反应堆对癌症患者进行治疗。截至1989年5月，78名患者接受了伽马 - 中子混合疗法及综合治疗（术前放射治疗和手术）。仅在42名单独接受根治性放射治疗的患者中有3名（7%）出现了明显的晚期局部反应（软骨膜炎）。43名患者的随访期为两年。其中，T2期肿瘤6例（14%），T3期28例（65%），T4期9例（21%）。13名（30%）患者出现区域转移。27名接受根治性伽马 - 中子治疗的患者中有19名（70%）存活两年且无疾病迹象，16名使用反应堆快中子作为术前放射治疗进行综合治疗的患者中有13名（81%）存活两年且无疾病迹象。
