经动脉化疗栓塞治疗肝细胞癌后发生的急性肿瘤溶解综合征。
Acute tumor lysis syndrome after transarterial chemoembolization for hepatocellular carcinoma.
作者信息
Shiba Hiroaki, Ishida Yuichi, Wakiyama Shigeki, Sakamoto Taro, Misawa Takeyuki, Yanaga Katsuhiko
机构信息
Department of Surgery, Jikei University School of Medicine, Tokyo, Japan.
出版信息
Cancer Sci. 2008 Oct;99(10):2104-5. doi: 10.1111/j.1349-7006.2008.00958.x.
Abstract
A 77-year-old-man was admitted to hospital for treatment of a huge hepatocellular carcinoma by transarterial chemoembolization. After treatment, the patient developed acute tumor lysis syndrome with hyperkalemia, hyperuricemia, hyperphosphatemia, hypocalcemia, metabolic acidosis and acute renal failure, which was successfully treated. In the treatments of solid organ tumors, acute tumor lysis syndrome is an extremely rare complication. To the best of the authors' knowledge, this patient is the third case of such a complication after transarterial chemoembolization for a hepatocellular carcinoma in the English literature.
摘要
一名77岁男性因巨大肝细胞癌接受经动脉化疗栓塞治疗入院。治疗后，患者出现急性肿瘤溶解综合征，伴有高钾血症、高尿酸血症、高磷血症、低钙血症、代谢性酸中毒和急性肾衰竭，经成功治疗。在实体器官肿瘤的治疗中，急性肿瘤溶解综合征是一种极其罕见的并发症。据作者所知，该患者是英文文献中经动脉化疗栓塞治疗肝细胞癌后出现这种并发症的第三例。
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