Ferreira Manuel A R, Purcell Shaun M
Department of Psychiatry, Massachusetts General Hospital, Boston, USA.
Bioinformatics. 2009 Jan 1;25(1):132-3. doi: 10.1093/bioinformatics/btn563. Epub 2008 Nov 19.
Although genetic association studies often test multiple, related phenotypes, few formal multivariate tests of association are available. We describe a test of association that can be efficiently applied to large population-based designs.
A C++ implementation can be obtained from the authors.
尽管基因关联研究常常测试多个相关的表型,但可用的正式多变量关联测试却很少。我们描述了一种关联测试,它可以有效地应用于基于大人群的设计。
可以从作者处获得C++实现。