Ginsberg Jeremy, Mohebbi Matthew H, Patel Rajan S, Brammer Lynnette, Smolinski Mark S, Brilliant Larry
Google Inc., 1600 Amphitheatre Parkway, Mountain View, California 94043, USA.
Nature. 2009 Feb 19;457(7232):1012-4. doi: 10.1038/nature07634.
Seasonal influenza epidemics are a major public health concern, causing tens of millions of respiratory illnesses and 250,000 to 500,000 deaths worldwide each year. In addition to seasonal influenza, a new strain of influenza virus against which no previous immunity exists and that demonstrates human-to-human transmission could result in a pandemic with millions of fatalities. Early detection of disease activity, when followed by a rapid response, can reduce the impact of both seasonal and pandemic influenza. One way to improve early detection is to monitor health-seeking behaviour in the form of queries to online search engines, which are submitted by millions of users around the world each day. Here we present a method of analysing large numbers of Google search queries to track influenza-like illness in a population. Because the relative frequency of certain queries is highly correlated with the percentage of physician visits in which a patient presents with influenza-like symptoms, we can accurately estimate the current level of weekly influenza activity in each region of the United States, with a reporting lag of about one day. This approach may make it possible to use search queries to detect influenza epidemics in areas with a large population of web search users.
季节性流感疫情是一个重大的公共卫生问题,每年在全球导致数千万例呼吸道疾病,以及25万至50万人死亡。除了季节性流感外,一种此前不存在免疫力且能在人际间传播的新型流感病毒可能引发一场造成数百万人死亡的大流行。疾病活动的早期发现,若随后能迅速做出反应,可减轻季节性流感和大流行性流感的影响。改善早期发现的一种方法是通过监测以向在线搜索引擎提交查询的形式出现的就医行为,全球每天有数百万用户提交此类查询。在此,我们展示一种分析大量谷歌搜索查询以追踪人群中流感样疾病的方法。由于某些查询的相对频率与出现流感样症状的患者就诊百分比高度相关,我们能够准确估计美国每个地区每周流感活动的当前水平,报告延迟约为一天。这种方法可能使利用搜索查询在大量网络搜索用户所在地区检测流感疫情成为可能。