Carruthers Alastair, Carruthers Jean, Hardas Bhushan, Kaur Mandeep, Goertelmeyer Roman, Jones Derek, Rzany Berthold, Cohen Joel, Kerscher Martina, Flynn Timothy Corcoran, Maas Corey, Sattler Gerhard, Gebauer Alexander, Pooth Rainer, McClure Kathleen, Simone-Korbel Ulli, Buchner Larry
Department of Dermatology and Skin Sciences, University of British Columbia, Vancouver, British Columbia, Canada.
Dermatol Surg. 2008 Nov;34 Suppl 2:S155-60. doi: 10.1111/j.1524-4725.2008.34364.x.
As with other facial wrinkles, the gradual loss and disorganization of collagen fibers and elastin, connective tissues that provide underlying support for skin, cause horizontal forehead rhytides in large part.
To develop the Forehead Lines Grading Scale for objective quantification of horizontal forehead rhytides at rest and with expression and to establish the reliability of this photonumeric scale for clinical research and practice.
The Forehead Lines Grading Scale is a 5-point photonumeric rating scale that was developed to objectively quantify resting (static) and hyperkinetic (dynamic) forehead lines. Inter- and intrarater variability was assessed by computing intraclass correlation coefficients.
The agreement between the experts was highly significant. Bubble plots (bivariate scatter plots) demonstrated linearity in judgment by the experts.
The 5-point photonumeric scale generated spans the severity of forehead lines for which patients commonly seek correction. The scale is well stratified for consistent rating.
与其他面部皱纹一样，胶原蛋白纤维和弹性蛋白（为皮肤提供支撑的结缔组织）的逐渐流失和紊乱在很大程度上导致了前额横纹的出现。
制定前额纹分级量表，以客观量化静息状态和表情状态下的前额横纹，并确定该数字量表在临床研究和实践中的可靠性。
前额纹分级量表是一个5分的数字量表，用于客观量化静息（静态）和运动过度（动态）前额纹。通过计算组内相关系数评估评分者间和评分者内的变异性。
专家之间的一致性非常显著。气泡图（双变量散点图）显示专家判断具有线性关系。
生成的5分数字量表涵盖了患者通常寻求矫正的前额纹严重程度范围。该量表分层良好，可进行一致评分。
