Ponte Maya, Klemperer Erika, Sahay Anju, Chren Mary-Margaret
School of Medicine, University of California-San Francisco, San Francisco, California, USA.
J Am Acad Dermatol. 2009 Jan;60(1):70-6. doi: 10.1016/j.jaad.2008.06.032. Epub 2008 Nov 20.
The experiences of women with vulvodynia are poorly understood.
We sought to determine the effects of vulvodynia on quality of life.
We conducted a survey of 280 patients in a university-based vulvar disorders clinic. Skin-related quality of life was measured with a vulvar-specific version of Skindex-29.
The response rate was 95%; 101 patients (36%) had vulvodynia, and 179 patients (64%) had other vulvar conditions. Women with vulvodynia had significantly worse quality of life than patients with many other dermatologic conditions, and worse functioning than women with other vulvar conditions (mean functioning scores [+/-SD] of patients with psoriasis, other vulvar conditions, and vulvodynia were 23 +/- 27, 34 +/- 24, and 44 +/- 22, respectively, P = .05). A diagnosis of vulvodynia was the strongest independent correlate of poor quality of life (eg, for poor functioning, odds ratio = 1.8, 95% confidence interval 1.0-3.1).
Limitations are single academic medical center and comorbid illnesses determined by self-report.
Vulvodynia has broad and substantial effects on quality of life.
人们对患有外阴痛的女性的经历了解甚少。
我们试图确定外阴痛对生活质量的影响。
我们对一家大学外阴疾病诊所的280名患者进行了调查。使用Skindex-29的外阴特定版本测量与皮肤相关的生活质量。
应答率为95%；101名患者（36%）患有外阴痛，179名患者（64%）患有其他外阴疾病。患有外阴痛的女性的生活质量明显比许多其他皮肤病患者差，其功能比患有其他外阴疾病的女性差（银屑病患者、其他外阴疾病患者和外阴痛患者的平均功能评分[±标准差]分别为23±27、34±24和44±22，P = 0.05）。外阴痛的诊断是生活质量差的最强独立相关因素（例如，对于功能差，比值比 = 1.8，95%置信区间1.0 - 3.1）。
局限性在于单一学术医学中心以及通过自我报告确定的共病。
外阴痛对生活质量有广泛而重大的影响。
