中耳炎在实验台和临床方面的进展。
Bench and bedside advances in otitis media.
作者信息
Kerschner Joseph E
机构信息
Division of Pediatric Otolaryngology, Department of Otolaryngology and Communication Sciences, MedicalCollege of Wisconsin, Children's Hospital of Wisconsin, Milwaukee, Wisconsin 53226, USA.
出版信息
Curr Opin Otolaryngol Head Neck Surg. 2008 Dec;16(6):543-7. doi: 10.1097/moo.0b013e328318448c.
PURPOSE OF REVIEW
Otitis media continues to be an important pediatric illness and requires significant expenditures in management and treatment. Despite its prevalence and importance, clinicians often have significant knowledge deficits regarding the most up-to-date research or clinical thinking regarding this disease. The present review aims to discuss recent and important publications related to otitis media and present an analysis of some of these findings.
RECENT FINDINGS
Major basic science and clinical themes related to otitis media are discussed and include the importance of biofilms in otitis media pathogenesis, the evidence that otitis media with effusion impacts development, the impact of otitis media treatment on quality of life, risk factors associated with otitis media and current concepts with respect to vaccine strategies and otitis media.
SUMMARY
Important basic and clinical research in the field of otitis media continues to clarify our understanding of the pathogenesis of this disease and drive new paradigms in treatment and clinical management.
综述目的
中耳炎仍是一种重要的儿科疾病，在管理和治疗方面需要大量支出。尽管其患病率高且很重要，但临床医生对于该疾病的最新研究或临床思路往往存在重大知识欠缺。本综述旨在讨论与中耳炎相关的近期重要出版物，并对其中一些研究结果进行分析。
近期发现
讨论了与中耳炎相关的主要基础科学和临床主题，包括生物膜在中耳炎发病机制中的重要性、中耳积液影响发育的证据、中耳炎治疗对生活质量的影响、与中耳炎相关的风险因素以及当前关于疫苗策略和中耳炎的概念。
总结
中耳炎领域的重要基础和临床研究不断深化我们对该疾病发病机制的理解，并推动治疗和临床管理的新范式。
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