Hamdan Ashraf, Thouet Thomas, Kelle Sebastian, Paetsch Ingo, Gebker Rolf, Wellnhofer Ernst, Schnackenburg Bernhard, Fahmy Ahmed S, Osman Nael F, Fleck Eckart
Department of Internal Medicine/Cardiology, Deutsches Herzzentrum Berlin, Berlin, Germany.
J Magn Reson Imaging. 2008 Dec;28(6):1379-85. doi: 10.1002/jmri.21526.
To prospectively determine the feasibility and accuracy of strain-encoded (SENC) magnetic resonance imaging (MRI) for the characterization of the right ventricular free wall (RVFW) strain and timing of contraction at 3.0 Tesla (3T) MRI.
In 12 healthy volunteers the RVFW was divided into three segments (anterior, lateral, and inferior) in each of three short-axis (SA) slices (apical, mid, and basal) and into three segments (apical, mid, and basal) in a four-chamber view. The study was repeated on a different day and interobserver and interstudy agreements were evaluated.
Maximal systolic longitudinal strain values were highest at the apex and base, with a pronounced decrease in the medial segments (apex: -19.1% +/- 1.4; mid: -17.4% +/- 2; base: -19.4% +/- 2.4, P < 0.001), and maximal systolic circumferential strain showed the highest values at the apex (apex: -18.1% +/- 1.7; mid: -17.6% +/- 1.2; base: -16.6% +/- 0.9, P < 0.001). Peak systolic longitudinal and circumferential shortening occurred earliest at the apex compared to the mid-ventricle and base. Excellent interobserver and interstudy correlation and agreement were observed.
The use of SENC MRI for the assessment of normal RV contraction pattern is feasible and accurate in 3T MRI.
前瞻性地确定应变编码（SENC）磁共振成像（MRI）在3.0特斯拉（3T）MRI中用于表征右心室游离壁（RVFW）应变及收缩时间的可行性和准确性。
在12名健康志愿者中，在三个短轴（SA）切片（心尖、中间和基底）的每一个中，将RVFW分为三个节段（前壁、侧壁和下壁），并在四腔视图中将其分为三个节段（心尖、中间和基底）。在不同日期重复该研究，并评估观察者间和研究间的一致性。
最大收缩期纵向应变值在心尖和基底处最高，中间节段明显降低（心尖：-19.1%±1.4；中间：-17.4%±2；基底：-19.4%±2.4，P<0.001），最大收缩期圆周应变在心尖处显示最高值（心尖：-18.1%±1.7；中间：-17.6%±1.2；基底：-16.6%±0.9，P<0.001）。与心室中部和基底相比，心尖处最早出现收缩期纵向和圆周缩短的峰值。观察到观察者间和研究间具有出色的相关性和一致性。
在3T MRI中，使用SENC MRI评估正常RV收缩模式是可行且准确的。
