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卡泊芬净与两性霉素B联合对光滑念珠菌的抗真菌活性：纸片扩散法、Etest法和时间杀菌法的比较

Antifungal activity of caspofungin in combination with amphotericin B against Candida glabrata: comparison of disk diffusion, Etest, and time-kill methods.

作者信息

Kiraz Nuri, Dag Ilknur, Yamac Mustafa, Kiremitci Abdurrahman, Kasifoglu Nilgun, Akgun Yurdanur

机构信息

Department of Microbiology, University of Osmangazi, Eskişehir, Turkey.

出版信息

Antimicrob Agents Chemother. 2009 Feb;53(2):788-90. doi: 10.1128/AAC.01131-08. Epub 2008 Nov 24.

DOI:10.1128/AAC.01131-08
PMID:19029317
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2630607/
Abstract

The in vitro activities of caspofungin plus amphotericin B against 50 Candida glabrata isolates were evaluated by the time-kill, disk diffusion, and Etest methods. In vitro experiments showed a positive interaction. Even though each of these methods uses different conditions and endpoints, the results of the different methods frequently agreed.

摘要

采用时间杀菌法、纸片扩散法和Etest法评估了卡泊芬净联合两性霉素B对50株光滑念珠菌分离株的体外活性。体外实验显示出正性相互作用。尽管这些方法中的每一种都使用不同的条件和终点，但不同方法的结果常常一致。

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