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不同方法测定氟康唑与三氯生体外抗氟康唑耐药白念珠菌临床分离株的相互作用。

In vitro interaction between fluconazole and triclosan against clinical isolates of fluconazole-resistant Candida albicans determined by different methods.

机构信息

Laboratory of Nutrition and Functional Food, Jilin University, Changchun, China.

出版信息

Antimicrob Agents Chemother. 2011 Jul;55(7):3609-12. doi: 10.1128/AAC.01313-10. Epub 2011 May 16.

DOI:10.1128/AAC.01313-10
PMID:21576450
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3122452/
Abstract

The in vitro interaction between triclosan and fluconazole against 24 azole-resistant clinical isolates of Candida albicans was evaluated by the microdilution checkerboard technique. The synergisms were verified by time-killing curves and agar diffusion tests in selected strains. Antagonistic activity was not detected.

摘要

采用微量棋盘稀释法评估了三氯生和氟康唑对 24 株唑类耐药白念珠菌临床分离株的体外相互作用。在选定的菌株中，通过时间杀伤曲线和琼脂扩散试验验证了协同作用。未检测到拮抗活性。

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J Med Microbiol. 2009 Aug;58(Pt 8):1074-1079. doi: 10.1099/jmm.0.008052-0. Epub 2009 Jun 15.
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J Antimicrob Chemother. 2009 Jul;64(1):88-93. doi: 10.1093/jac/dkp158. Epub 2009 May 14.
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Antimicrob Agents Chemother. 2009 Feb;53(2):788-90. doi: 10.1128/AAC.01131-08. Epub 2008 Nov 24.
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AIDS Patient Care STDS. 2008 Aug;22(8):613-8. doi: 10.1089/apc.2007.0160.
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