[氢化可的松和胰岛素对大鼠肝脏细胞结构中酪氨酸-α-酮戊二酸转氨酶活性及同工酶的影响]
[The effect of hydrocortisone and insulin on the activity and isoenzyme of tyrosine-alpha-ketoglutarate transaminase in cytostructures of rat liver].
作者信息
Polikarpova L I
出版信息
Vopr Med Khim. 1975 May-Jun;21(3):313-7.
PMID:1903
Abstract
Single administration of hydrocortisone or insulin into rats (body weight 200 g) and also combined treatment of the animals with the hormones at large doses caused a distinct increase in activities of anode and cathode isoenzymes of tyrosine-alpha-ketoglutarate transaminase in soluble fraction; total activity of the enzyme was also increased in mitochondria of rat liver tissue.
摘要
给体重200克的大鼠单次注射氢化可的松或胰岛素，以及用大剂量激素对动物进行联合治疗，均导致可溶性部分酪氨酸-α-酮戊二酸转氨酶阳极和阴极同工酶的活性显著增加；大鼠肝脏组织线粒体中该酶的总活性也有所增加。
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