干扰素抑制小鼠白血病病毒释放：一项电子显微镜研究。
Interferon inhibits mouse leukaemia virus release: an electron microscope study.
作者信息
Chang E H, Mims S J, Triche T J, Friedman R M
出版信息
J Gen Virol. 1977 Feb;34(2):363-7. doi: 10.1099/0022-1317-34-2-363.
PMID:190348
Abstract
Scanning electron microscopy of AKR cells chronically infected with AKR mouse leukaemia virus revealed that the number of budding virions was greatly increased in interferon-treated cells. These results, together with previous biochemical findings, suggest that in this system, interferon inhibits a late stage of virus assembly or release.
摘要
对长期感染AKR小鼠白血病病毒的AKR细胞进行扫描电子显微镜检查发现，在干扰素处理的细胞中，出芽病毒粒子的数量大幅增加。这些结果与之前的生化研究结果共同表明，在这个系统中，干扰素抑制病毒组装或释放的后期阶段。
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