This research was conducted as a descriptive study for the purpose of examining nurses' sleep quality, job satisfaction, and the relationship between them. The research population was comprised of nurses who work at Inönü University Turgut Ozal Medical Center (Turkey) and the research was conducted with a total of 418 nurses. A Personal Information Form, developed by the researchers based on information in the literature, and the Pittsburgh Sleep Quality Index (PSQI) and Short Form Minnesota Satisfaction Questionnaire (MSQ), which have been adapted for Turkish and had validity and reliability studies conducted, were used for data collection in the research. For data analysis, frequency distribution, arithmetic mean, variance analysis (One-Way ANOVA), Tukey test, and Independent Samples t test were used. According to the findings obtained from the research it was determined that nurses' total sleep quality score mean was 7.28 +/- 3.56 and job satisfaction score mean was 48.05 +/- 11.77 and a weak negative correlation was found between the 2 tools (r = -0.25) (P < .05). As the nurses' sleep quality increased (that is, as their sleep quality score mean decreased) their job satisfaction increased (their job satisfaction score mean increased). In general, the results obtained from our research show that nurses' sleep quality is low and their job satisfaction is at a moderate level. In parallel with this, as the nurses' sleep quality decreases their job satisfaction also decreases.