Li Xue-Zhi, Liu Xu-Guang, Song Wen-Zhong, Tang Yong, Zeng Fang, Liang Fan-Rong
College of Acupuncture and Massage, Chengdu University of TCM, Chengdu, Sichuan 610075, China.
Zhongguo Zhen Jiu. 2008 Nov;28(11):854-9.
To observe response characteristics of human brain to acupuncture of corresponding channel point selection and probe into the central nervous mechanism of acupuncture at the points selected along channel.
Six cases of chronic migraine were treated with acupuncture at Fengchi (GB 20), Waiguan (TE 5), Yang-lingquan (GB 34) on the Shaoyang Channel. Positron emission computerized tomography (PET-CT) was used for scanning and statistic parameter map (SPM 2) software was used to analyze the data and compare with healthy human brain function imaging and investigate the changes of metabolism of glucose in the brain of the patient of migraine before and after acupuncture.
After acupuncture, excitation areas of the pain brain regions such as the brain stem, insula, etc. obviously reduced, and the brain function-reducing area turned from the right temporal lobe as main to bilateral temporal lobes with symmetry.
The pons, insula, anterior frontal gyrus, etc. possibly are the target points of analgesic effect of acupuncture at the Shaoyang Channel on chronic migraine, and the change of metabolism reduction on bilateral temporal lobes induced by acupuncture possibly is one of the mechanisms for acu-puncture at points on the Shaoyang Channel for treatment of migraine. Acupuncture achieves whole and beneficial therapeutic effect possibly through coordination and redistribution of energy metabolism in the brain.
观察人脑对循经取穴针刺的反应特征，探讨循经取穴针刺的中枢神经机制。
选取6例慢性偏头痛患者，针刺少阳经的风池（GB 20）、外关（TE 5）、阳陵泉（GB 34）。采用正电子发射计算机断层显像（PET-CT）进行扫描，运用统计参数图（SPM 2）软件分析数据，并与健康人脑功能成像进行比较，观察偏头痛患者针刺前后脑内葡萄糖代谢的变化。
针刺后，脑干、脑岛等疼痛脑区的兴奋区域明显减少，脑功能减低区由以右侧颞叶为主转变为双侧颞叶对称。
脑桥、脑岛、额前回等可能是少阳经穴位针刺治疗慢性偏头痛的镇痛靶点，针刺引起双侧颞叶代谢减低的变化可能是少阳经穴位治疗偏头痛的机制之一。针刺可能通过脑内能量代谢的协调与重新分布而达到整体良性治疗效应。
