Ikeda Hiroki, Hamamoto Yoshiyuki, Honjo Sachiko, Nabe Koichiro, Wada Yoshiharu, Koshiyama Hiroyuki
Center for Diabetes & Endocrinology, The Tazuke Kofukai Foundation Medical Research Institute Kitano Hospital, Osaka, Japan.
Diabetes Res Clin Pract. 2009 Jan;83(1):117-8. doi: 10.1016/j.diabres.2008.10.013. Epub 2008 Dec 5.
We investigated the effect of olmesartan on early diabetic nephropathy in hypertensive patients with type 2 diabetes by its replacement of other angiotensin II type 1 receptor blockers (ARBs) by olmesartan. The urinary albumin/creatinine ratio significantly decreased. The present result suggests a possibility that olmesartan may have more effect on early nephropathy than other ARBs.
我们通过用奥美沙坦替代其他1型血管紧张素II受体阻滞剂(ARB),研究了奥美沙坦对2型糖尿病高血压患者早期糖尿病肾病的影响。尿白蛋白/肌酐比值显著降低。目前的结果表明,奥美沙坦可能比其他ARB对早期肾病有更大的影响。