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头孢吡肟单独及联合使用对囊性纤维化患者铜绿假单胞菌和洋葱伯克霍尔德菌临床分离株的比较活性。

Comparative activity of cefepime, alone and in combination, against clinical isolates of Pseudomonas aeruginosa and Pseudomonas cepacia from cystic fibrosis patients.

作者信息

Bosso J A, Saxon B A, Matsen J M

机构信息

College of Pharmacy, University of Houston, Texas.

出版信息

Antimicrob Agents Chemother. 1991 Apr;35(4):783-4. doi: 10.1128/AAC.35.4.783.

Abstract

The comparative in vitro activity and synergy of cefepime were evaluated with clinical isolates of Pseudomonas aeruginosa and Pseudomonas cepacia from cystic fibrosis patients. The activity of cefepime, both alone and in combination, was comparable to those of other antibiotics. The clinical efficacy of cefepime in cystic fibrosis patients merits investigation.

摘要

对头孢吡肟与来自囊性纤维化患者的铜绿假单胞菌和洋葱伯克霍尔德菌临床分离株的体外活性及协同作用进行了比较评估。头孢吡肟单独使用及联合使用时的活性与其他抗生素相当。头孢吡肟在囊性纤维化患者中的临床疗效值得研究。

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