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脊柱原发性恶性肿瘤。

Primary malignant tumors of the spine.

作者信息

Sundaresan Narayan, Rosen Gerald, Boriani Stefano

机构信息

Mount Sinai Medical School, 1148 Fifth Avenue, New York, NY 10128, USA.

出版信息

Orthop Clin North Am. 2009 Jan;40(1):21-36, v. doi: 10.1016/j.ocl.2008.10.004.

DOI:10.1016/j.ocl.2008.10.004
PMID:19064053
Abstract

Primary malignant tumors of the spine account for less than 5% of primary bone tumors. Data from the SEER program suggest that the most common bone sarcomas are osteosarcoma, chondrosarcoma, Ewing's sarcoma, chordoma, and malignant fibrous histiocytoma/fibrosarcoma. During the last two decades, tremendous progress has been made in clinical aspects, surgical approaches, and reconstruction with instrumentation at all levels of the spine. Stabilization procedures, including vertebroplasty and kyphoplasty, have further allowed palliation of pain and symptom relief from compression fractures. Improved radiation techniques have offered the potential for improved local control. This article reviews the changes in surgical philosophy in the management of malignant spinal tumors during the past two decades.

摘要

脊柱原发性恶性肿瘤占原发性骨肿瘤的比例不到5%。监测、流行病学与最终结果(SEER)项目的数据表明,最常见的骨肉瘤包括骨肉瘤、软骨肉瘤、尤因肉瘤、脊索瘤以及恶性纤维组织细胞瘤/纤维肉瘤。在过去二十年中,脊柱各个层面在临床、手术方法以及器械重建方面均取得了巨大进展。包括椎体成形术和后凸成形术在内的稳定手术,进一步实现了缓解疼痛以及减轻压缩性骨折症状的目的。改进后的放射技术提高了局部控制的可能性。本文回顾了过去二十年中恶性脊柱肿瘤治疗的手术理念变化。

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1
Primary malignant tumors of the spine.脊柱原发性恶性肿瘤。
Orthop Clin North Am. 2009 Jan;40(1):21-36, v. doi: 10.1016/j.ocl.2008.10.004.
2
Malignant bone tumors.恶性骨肿瘤
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Sarcoma and the spinal column.肉瘤与脊柱
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[Primary tumors of the spine. Initial oncologic aspects: epidemiology, anatomo-prognostic and therapeutic classification].[脊柱原发性肿瘤。肿瘤学初始方面:流行病学、解剖-预后及治疗分类]
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Association of surgical resection and survival in patients with malignant primary osseous spinal neoplasms from the Surveillance, Epidemiology, and End Results (SEER) database.来自监测、流行病学和最终结果(SEER)数据库的手术切除与恶性原发性骨脊柱肿瘤患者生存的关联。
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[SPINAL NEOPLASMS. II. MALIGNANT NEOPLASMS OF THE SPINE].[脊柱肿瘤。II. 脊柱恶性肿瘤]
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Health-related quality of life in patients treated with en bloc resection for primary tumors of the spine.
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Spinal chordoma and chondrosarcoma treatment experiences - a 20-year retrospective study from databases of two medical centers.脊柱脊索瘤和软骨肉瘤的治疗经验——来自两个医学中心数据库的 20 年回顾性研究。
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