Cahill Julian, Zhang John H
Division of Neurosurgery, Loma Linda University Medical Center, 11234 Anderson St, Room 2562B, Loma Linda, CA 92354, USA.
Stroke. 2009 Mar;40(3 Suppl):S86-7. doi: 10.1161/STROKEAHA.108.533315. Epub 2008 Dec 8.
Despite recent advances in the treatment of patients after subarachnoid hemorrhage, morbidity and mortality rates have failed to improve significantly. Although this was often blamed on vasospasm, is it time to consider alternative etiologies? Summary of Review- Early brain injury (EBI) is a recently described term that describes the immediate injury to the brain after subarachnoid hemorrhage. A number of pathways have been recognized as having a role in the etiology of EBI. This review provides a brief synopsis of EBI and its implications for the future.
EBI may be responsible for the detrimental effects seen in patients after subarachnoid hemorrhage. Additional studies are needed to determine the pathophysiology of EBI and to explore potential therapeutic options.
尽管蛛网膜下腔出血患者的治疗近来取得了进展，但发病率和死亡率仍未显著改善。虽然这通常归咎于血管痉挛，但现在是否该考虑其他病因了呢？综述总结——早期脑损伤（EBI）是一个最近描述的术语，用于描述蛛网膜下腔出血后大脑立即受到的损伤。已认识到多种途径在EBI的病因中起作用。本综述简要概述了EBI及其对未来的影响。
EBI可能是蛛网膜下腔出血患者出现有害影响的原因。需要进一步研究以确定EBI的病理生理学并探索潜在的治疗选择。
