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Isolation and properties of a Lyt-2.1-negative mutant of a Lyt-2.1/Lyt-2.2 CTL line.

作者信息

Chu Z T, Kung J T, Thomas C, Wall K A, Gottlieb P D

机构信息

Department of Microbiology, University of Texas, Austin 78712.

出版信息

Immunogenetics. 1991;34(1):42-51. doi: 10.1007/BF00212311.

DOI:10.1007/BF00212311
PMID:1906832
Abstract
摘要

相似文献

1
Isolation and properties of a Lyt-2.1-negative mutant of a Lyt-2.1/Lyt-2.2 CTL line.Lyt-2.1/Lyt-2.2细胞毒性T淋巴细胞系的Lyt-2.1阴性突变体的分离与特性
Immunogenetics. 1991;34(1):42-51. doi: 10.1007/BF00212311.
2
Role of accessory molecules in signal transduction of cytolytic T lymphocyte by anti-T cell receptor and anti-Ly-6.2C monoclonal antibodies.辅助分子在抗T细胞受体和抗Ly-6.2C单克隆抗体介导的细胞毒性T淋巴细胞信号转导中的作用
J Immunol. 1987 Dec 1;139(11):3556-63.
3
Transfection of the CD8 alpha gene restores specific target cell lysis: factors that determine the function and the expression of CD8 in a cytotoxic T cell clone.CD8α基因的转染可恢复特异性靶细胞裂解:决定细胞毒性T细胞克隆中CD8功能和表达的因素。
Int Immunol. 1990;2(3):247-56. doi: 10.1093/intimm/2.3.247.
4
Class II antigen-specific murine cytolytic T lymphocytes (CTL). II. Genuine class II specificity of Lyt-2+ CTL clones.II类抗原特异性小鼠细胞毒性T淋巴细胞(CTL)。II. Lyt-2+ CTL克隆的真正II类特异性。
J Immunol. 1988 Jan 1;140(1):30-6.
5
Effects of anti-Lyt-2 and anti-L3T4 monoclonal antibodies on the function of cytotoxic T lymphocyte/helper T lymphocyte hybrid T cell clones.抗Lyt-2和抗L3T4单克隆抗体对细胞毒性T淋巴细胞/辅助性T淋巴细胞杂交T细胞克隆功能的影响。
J Immunol. 1988 Sep 15;141(6):1808-12.
6
Blocking of CTL-mediated killing by monoclonal antibodies to LFA-1 and Lyt-2, 3. II. Evidence that trypsin pretreatment of target cells removes a non-H-2 molecule important in killing.用抗淋巴细胞功能相关抗原-1(LFA-1)和抗Lyt-2、3单克隆抗体阻断细胞毒性T淋巴细胞(CTL)介导的杀伤作用。II. 靶细胞经胰蛋白酶预处理可去除杀伤过程中起重要作用的非H-2分子的证据。
J Immunol. 1985 Jan;134(1):70-7.
7
Class II antigen-specific murine cytolytic T lymphocytes (CTL). I. Analysis of bulk populations and establishment of Lyt-2+L3T4- and Lyt-2-L3T4+ bulk CTL lines.II类抗原特异性小鼠细胞毒性T淋巴细胞(CTL)。I. 大量群体分析以及Lyt-2⁺L3T4⁻和Lyt-2⁻L3T4⁺大量CTL系的建立。
Cell Immunol. 1987 Jul;107(2):395-407. doi: 10.1016/0008-8749(87)90247-4.
8
A rat anti-mouse T4 monoclonal antibody (H129.19) inhibits the proliferation of Ia-reactive T cell clones and delineates two phenotypically distinct (T4+, Lyt-2,3-, and T4-, Lyt-2,3+) subsets among anti-Ia cytolytic T cell clones.一种大鼠抗小鼠T4单克隆抗体(H129.19)可抑制Ia反应性T细胞克隆的增殖,并在抗Ia细胞毒性T细胞克隆中区分出两个表型不同的亚群(T4+、Lyt-2,3-和T4-、Lyt-2,3+)。
J Immunol. 1984 Jun;132(6):2775-82.
9
Inhibition of helper function with anti-Lyt-2 or anti-L3T4 monoclonal antibodies depending on stimulating antigens.根据刺激抗原的不同,用抗Lyt-2或抗L3T4单克隆抗体抑制辅助功能。
Eur J Immunol. 1985 Dec;15(12):1187-91. doi: 10.1002/eji.1830151209.
10
Relationship among function, phenotype, and specificity in primary allospecific T cell populations: identification of phenotypically identical but functionally distinct primary T cell subsets that differ in their recognition of MHC class I and class II allodeterminants.原发性同种特异性T细胞群体中功能、表型和特异性之间的关系:鉴定表型相同但功能不同的原发性T细胞亚群,这些亚群在对MHC I类和II类同种异体决定簇的识别上存在差异。
J Immunol. 1987 Jan 1;138(1):10-7.

引用本文的文献

1
Differential susceptibility of mouse Lyt-2 and Lyt-3 genes to negative regulation.小鼠Lyt-2和Lyt-3基因对负调控的差异敏感性。
Immunogenetics. 1993;37(2):129-34. doi: 10.1007/BF00216836.
2
Mutants of cultured mouse cells deficient in Ly-2 antigen.缺乏Ly-2抗原的培养小鼠细胞突变体。
Immunogenetics. 1994;40(2):154-8. doi: 10.1007/BF00188180.
3
Inducible functions in hybrids of a Lyt-2+ BW5147 transfectant and the 2C CTL line.Lyt-2+ BW5147转染细胞与2C细胞毒性T淋巴细胞系杂交体中的可诱导功能。

本文引用的文献

1
Construction and properties of new Lyt-congenic strains and anti-Lyt-2.2 and anti-Lyt-3.1 monoclonal antibodies.新型 Lyt 同基因株系的构建与特性,以及抗 Lyt-2.2 和抗 Lyt-3.1 单克隆抗体。
Immunogenetics. 1980;10(6):545-55. doi: 10.1007/BF01572589.
2
H-2 antigen variants in a cultured heterozygous mouse leukemia cell line. VI. Rate of emergence of the hemizygous variants and evidence that the variants preexist the selection.在培养的杂合子鼠白血病细胞系中 H-2 抗原变体。VI. 半合子变体出现的速度和变体先于选择存在的证据。
Immunogenetics. 1980;10(5):411-22. doi: 10.1007/BF01572577.
3
Anti-H-2 hybridoma antibodies as immunoselective agents. I. Isolation of forward and reverse mutations for reactivity with a monoclonal antibody.
Immunogenetics. 1992;36(5):283-93. doi: 10.1007/BF00215656.
抗H-2杂交瘤抗体作为免疫选择剂。I. 与单克隆抗体反应的正向和反向突变的分离。
Immunogenetics. 1981;14(3-4):253-62. doi: 10.1007/BF00342194.
4
Monoclonal antibodies to mouse MHC antigens. II. Antibodies to the H-2Ld antigen, the products of a third polymorphic locus of the mouse major histocompatibility complex.针对小鼠MHC抗原的单克隆抗体。II. 针对H-2Ld抗原的抗体,小鼠主要组织相容性复合体第三个多态性位点的产物
J Immunol. 1980 Dec;125(6):2473-7.
5
Clonal heterogeneity in the functional requirement for Lyt-2/3 molecules on cytolytic T lymphocytes: analysis by antibody blocking and selective trypsinization.细胞毒性T淋巴细胞上Lyt-2/3分子功能需求的克隆异质性:通过抗体阻断和选择性胰蛋白酶消化进行分析。
J Exp Med. 1982 Dec 1;156(6):1711-22. doi: 10.1084/jem.156.6.1711.
6
Alloreactive cloned T cell lines. I. Interactions between cloned amplifier and cytolytic T cell lines.同种异体反应性克隆T细胞系。I. 克隆扩增性T细胞系与细胞溶解性T细胞系之间的相互作用。
J Exp Med. 1980 Apr 1;151(4):876-95. doi: 10.1084/jem.151.4.876.
7
Lyt-2-/Lyt 3- variants of a cloned cytolytic T cell line lack an antigen receptor functional in cytolysis.一个克隆的细胞溶解T细胞系的Lyt-2-/Lyt 3-变体缺乏在细胞溶解中起作用的抗原受体。
J Exp Med. 1981 Mar 1;153(3):595-604. doi: 10.1084/jem.153.3.595.
8
H-2 haplotypes, genes and antigens: second listing. II. The H-2 complex.H-2单倍型、基因与抗原:第二次列表。二、H-2复合体
Immunogenetics. 1983;17(6):553-96. doi: 10.1007/BF00366126.
9
Monoclonal anti-Lyt-2.2 antibody blocks lectin-dependent cellular cytotoxicity of H-2-negative target cells.单克隆抗Lyt-2.2抗体可阻断H-2阴性靶细胞的凝集素依赖性细胞毒性。
J Exp Med. 1984 Feb 1;159(2):551-8. doi: 10.1084/jem.159.2.551.
10
T cell subsets and the recognition of MHC class.T细胞亚群与主要组织相容性复合体(MHC)类分子的识别
Immunol Rev. 1983;74:129-42. doi: 10.1111/j.1600-065x.1983.tb01087.x.