Gray Kevin M, LaRowe Steven D, Upadhyaya Himanshu P
Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston 29425, USA.
Psychol Addict Behav. 2008 Dec;22(4):582-6. doi: 10.1037/a0012985.
To develop and evaluate the feasibility of a cue reactivity paradigm for young marijuana smokers, the authors set up a laboratory procedure involving neutral and marijuana-related imagery, video, and in vivo cues. Fifteen adolescents and young adults with cannabis use disorders completed the procedure, which included continuous measurement of skin conductance and heart rate. Participants also completed questionnaires regarding marijuana craving before, during, and after cue presentations. Higher levels of craving and skin conductance were observed during marijuana cue presentations. The procedure appears to elicit cue reactivity among adolescents and young adults with cannabis use disorders and should be further evaluated and refined with a larger sample. Implications for future studies are discussed.
为了开发和评估针对年轻大麻吸食者的线索反应范式的可行性,作者建立了一个实验室程序,其中涉及中性和与大麻相关的图像、视频及现场线索。15名患有大麻使用障碍的青少年和年轻人完成了该程序,该程序包括持续测量皮肤电导率和心率。参与者还在线索呈现之前、期间和之后完成了关于大麻渴望的问卷调查。在呈现大麻线索期间,观察到更高水平的渴望和皮肤电导率。该程序似乎能在患有大麻使用障碍的青少年和年轻人中引发线索反应,应该用更大的样本进一步评估和完善。文中还讨论了对未来研究的启示。