Jern P, Santtila P, Johansson A, Varjonen M, Witting K, von der Pahlen B, Sandnabba N K
Department of Psychology, Center of Excellence in Behavior Genetics, Abo Akademi University, Turku, Finland.
Int J Impot Res. 2009 Jan-Feb;21(1):62-7. doi: 10.1038/ijir.2008.61. Epub 2008 Dec 11.
A number of theoretical approaches to understanding the etiology of ejaculatory dysfunction have been proposed, but no study has yet found conclusive evidence that premature (PE) or delayed (DE) ejaculation is under genetic control. We conducted twin model fitting analyses on different indicator variables of ejaculatory function on a population-based sample of 3946 twins and their siblings (age 18-48; mean=29.9 years) to investigate genetic, shared environmental and unique environmental effects on PE and DE. A significant moderate genetic effect (28%) was found for PE. No clear-cut familial effect could be detected for DE. Significant associations between ejaculatory function and age were detected, but effects of age were generally very weak. The findings from the present study provide useful information regarding the etiology and understanding of ejaculatory dysfunction.
为了理解射精功能障碍的病因，人们已经提出了多种理论方法，但尚无研究找到确凿证据表明早泄（PE）或射精延迟（DE）受基因控制。我们对3946对双胞胎及其兄弟姐妹（年龄18 - 48岁；平均29.9岁）的群体样本的射精功能不同指标变量进行了双生子模型拟合分析，以研究基因、共同环境和独特环境对早泄和射精延迟的影响。研究发现早泄存在显著的中等程度基因效应（28%）。对于射精延迟，未检测到明确的家族效应。检测到射精功能与年龄之间存在显著关联，但年龄的影响通常非常微弱。本研究结果为射精功能障碍的病因及理解提供了有用信息。
