Brandtzaeg P, Kiyono H, Pabst R, Russell M W
Department of Pathology, Rikshospitalet University Hospital, Oslo, Norway.
Mucosal Immunol. 2008 Jan;1(1):31-7. doi: 10.1038/mi.2007.9.
Stimulation of mucosal immunity has great potential in vaccinology and immunotherapy. However, the mucosal immune system is more complex than the systemic counterpart, both in terms of anatomy (inductive and effector tissues) and effectors (cells and molecules). Therefore, immunologists entering this field need a precise terminology as a crucial means of communication. Abbreviations for mucosal immune-function molecules related to the secretory immunoglobulin A system were defined by the Society for Mucosal Immunolgy Nomenclature Committee in 1997, and are briefly recapitulated in this article. In addition, we recommend and justify standard nomenclature and abbreviations for discrete mucosal immune-cell compartments, belonging to, and beyond, mucosa-associated lymphoid tissue.
黏膜免疫刺激在疫苗学和免疫治疗中具有巨大潜力。然而,黏膜免疫系统在解剖结构(诱导和效应组织)和效应器(细胞和分子)方面都比全身免疫系统更为复杂。因此,进入该领域的免疫学家需要精确的术语作为关键的交流手段。与分泌型免疫球蛋白A系统相关的黏膜免疫功能分子的缩写由黏膜免疫学会命名委员会于1997年定义,本文将简要概述。此外,我们推荐并论证了属于黏膜相关淋巴组织及之外的离散黏膜免疫细胞区室的标准命名法和缩写。