Tannock G W
Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand.
Mucosal Immunol. 2008 Nov;1 Suppl 1:S15-8. doi: 10.1038/mi.2008.54.
Nucleic acid-based (molecular) analytical methods have utility in discriminating between bowel microbiota of altered compositions. This has been demonstrated in studies involving both experimental animals and humans with inflammation of the bowel. Although alterations in the composition of the microbiota can be demonstrated, future studies need to provide functional links between the candidate proinflammatory agents and disease processes.
基于核酸的(分子)分析方法在鉴别组成改变的肠道微生物群方面具有实用性。这一点已在涉及实验动物和患有肠道炎症的人类的研究中得到证实。虽然微生物群的组成变化可以得到证明,但未来的研究需要提供候选促炎因子与疾病过程之间的功能联系。