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本文引用的文献

1
HIGHLY STEREOSELECTIVE REDUCTION OF α-KETO ESTERS: UTILITY OF CIS-1-ARYLSULFONAMIDO-2-INDANOLS AS CHIRAL AUXILIARIES.α-酮酯的高度立体选择性还原：顺式-1-芳基磺酰胺基-2-茚醇作为手性助剂的应用
Tetrahedron Lett. 1995 Sep 18;36(38):6811-6814. doi: 10.1016/0040-4039(95)01385-U. Epub 2000 Jun 14.
2
Base-catalysed asymmetric hydroamination/cyclisation of aminoalkenes utilising a dimeric chiral diamidobinaphthyl dilithium salt.
Chem Commun (Camb). 2006 Jun 4(21):2221-3. doi: 10.1039/b518360j. Epub 2006 Apr 11.
3
Palladium-catalyzed intramolecular asymmetric hydroamination, hydroalkoxylation, and hydrocarbonation of alkynes.钯催化的炔烃分子内不对称氢胺化、氢烷氧基化和烃化反应。
J Org Chem. 2006 May 26;71(11):4270-9. doi: 10.1021/jo0603835.
4
3,3'-Bis(trisarylsilyl)-substituted binaphtholate rare earth metal catalysts for asymmetric hydroamination.用于不对称氢胺化反应的3,3'-双（三芳基硅基）取代的联萘酚稀土金属催化剂
J Am Chem Soc. 2006 Mar 22;128(11):3748-59. doi: 10.1021/ja058287t.
5
Enantioselective intramolecular hydroamination catalyzed by lanthanide ate complexes coordinated by N-substituted (R)-1,1'-binaphthyl-2,2'-diamido ligands.
J Org Chem. 2006 Mar 17;71(6):2514-7. doi: 10.1021/jo052322x.
6
Intramolecular alkene hydroaminations catalyzed by a bis(thiophosphinic amidate) Zr(IV) complex.双（硫代次膦酸酰胺）Zr(IV) 配合物催化的分子内烯烃氢胺化反应
Chem Commun (Camb). 2005 Nov 7(41):5205-7. doi: 10.1039/b505738h. Epub 2005 Sep 20.
7
Catalytic asymmetric hydroamination of non-activated olefins.非活化烯烃的催化不对称氢胺化反应。
Org Biomol Chem. 2005 May 21;3(10):1819-24. doi: 10.1039/b418521h. Epub 2005 Apr 7.
8
Intramolecular hydroamination of unactived olefins with Ti(NMe2)4 as a precatalyst.
Org Lett. 2005 May 12;7(10):1959-62. doi: 10.1021/ol0503992.
9
Enantioselective intramolecular alkene hydroaminations catalyzed by yttrium complexes of axially chiral bis(thiolate) ligands.轴手性双（硫醇盐）配体的钇配合物催化的对映选择性分子内烯烃氢胺化反应。
Org Lett. 2005 Apr 28;7(9):1737-9. doi: 10.1021/ol050294z.
10
Lanthanide complexes coordinated by N-substituted (R)-1,1'-binaphthyl-2,2'-diamido ligands in the catalysis of enantioselective intramolecular hydroamination.由N-取代的（R）-1,1'-联萘-2,2'-二氨基配体配位的镧系元素配合物在对映选择性分子内氢胺化催化中的应用
Chemistry. 2005 May 20;11(11):3455-62. doi: 10.1002/chem.200401203.

用于不对称分子内烯烃氢胺化反应的双（酰胺基）锆催化剂

Zirconium Bis(Amido) Catalysts for Asymmetric Intramolecular Alkene Hydroamination.

作者信息

Watson Donald A, Chiu Melanie, Bergman Robert G

机构信息

Department of Chemistry, University of California, Berkeley, California 94720-1460,

出版信息

Organometallics. 2006 Sep 25;25(20):4731-4733. doi: 10.1021/om0606791.

DOI:10.1021/om0606791
PMID:19079735
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2600731/
Abstract

In situ combination of diphosphinic amides and Zr(NMe(2))(4) results in the formation of chiral zirconium bis(amido) complexes. The complexes are competent catalysts for intramolecular asymmetric alkene hydroamintion, providing piperidines and pyrrolidines in up to 80% ee and high yield. This system utilizes an inexpensive zirconium precatalyst and readily prepared ligands and is the first asymmetric alkene hydroamination catalyst based upon a neutral zirconium bis(amido) complex.

摘要

二膦酰胺与Zr(NMe(2))(4)的原位组合导致手性双（酰胺基）锆配合物的形成。这些配合物是分子内不对称烯烃氢胺化反应的有效催化剂，能以高达80%的对映体过量和高产率提供哌啶和吡咯烷。该体系使用一种廉价的锆预催化剂和易于制备的配体，是首个基于中性双（酰胺基）锆配合物的不对称烯烃氢胺化催化剂。