Li Youzhi, Zhang Huiliang, Kim Chulhong, Wagner Kelvin H, Hemmer Philip, Wang Lihong V
Appl Phys Lett. 2008 Jul 7;93(1):11111. doi: 10.1063/1.2952489. Epub 2008 Jul 11.
We applied a submegahertz nonlinear optical filter afforded by a cryogenically cooled spectral-hole burning crystal to ultrasound-modulated optical tomography. Our experimental results show that this technique, having the largest etendue among all available ultrasound-modulated optical tomography techniques and being immune to speckle decorrelation, offers potential for imaging in vivo and forming high resolution optical tomograms in real time. It opens an opportunity for the development of a clinically applicable high resolution optical imaging modality.
我们将由低温冷却的光谱烧孔晶体提供的亚兆赫兹非线性光学滤波器应用于超声调制光学层析成像。我们的实验结果表明，该技术在所有可用的超声调制光学层析成像技术中具有最大的 étendue，并且不受散斑去相关的影响，具有体内成像和实时形成高分辨率光学层析图像的潜力。它为开发临床适用的高分辨率光学成像模态提供了机会。
