Brébion G, David A S, Bressan R A, Ohlsen R I, Pilowsky L S
Department of Psychiatry, Institute of Psychiatry, King's College, London, UK.
Psychol Med. 2009 Jun;39(6):917-26. doi: 10.1017/S0033291708004819. Epub 2008 Dec 11.
Previous research has demonstrated that various types of verbal source memory error are associated with positive symptoms in patients with schizophrenia. Notably, intrusions in free recall have been associated with hallucinations and delusions. We tested the hypothesis that extra-list intrusions, assumed to arise from poor monitoring of internally generated words, are associated with verbal hallucinations and that intra-list intrusions are associated with global hallucination scores.
A sample of 41 patients with schizophrenia was administered four lists of words, followed by free recall. The number of correctly recalled words and the number of extra- and intra-list intrusions were tallied.
The verbal hallucination score was significantly correlated with the number of extra-list intrusions, whereas it was unrelated to the number of correctly recalled words. The number of intra-list intrusions was significantly correlated with the global, but not with the verbal, hallucination score in the subsample of hallucinating patients. It was marginally significantly correlated with the delusion score in delusional patients.
The data corroborate the view that verbal hallucinations are linked to defective monitoring of internal speech, and that errors in context processing are involved in hallucinations and delusions.
先前的研究表明，精神分裂症患者的各种言语源记忆错误与阳性症状相关。值得注意的是，自由回忆中的侵入与幻觉和妄想有关。我们检验了以下假设：假定由对内部产生的词语监测不佳引起的列表外侵入与言语幻觉相关，而列表内侵入与整体幻觉评分相关。
对41名精神分裂症患者样本进行四组词的记忆测试，随后进行自由回忆。统计正确回忆的词数以及列表外和列表内侵入的数量。
言语幻觉评分与列表外侵入的数量显著相关，而与正确回忆的词数无关。在有幻觉的患者子样本中，列表内侵入的数量与整体幻觉评分显著相关，但与言语幻觉评分无关。在有妄想的患者中，它与妄想评分呈边缘显著相关。
数据证实了以下观点，即言语幻觉与内部言语监测缺陷有关，且上下文处理错误与幻觉和妄想有关。
