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脉冲电磁场治疗骨质疏松症的临床进展

Clinical update of pulsed electromagnetic fields on osteoporosis.

作者信息

Huang Li-qun, He Hong-chen, He Cheng-qi, Chen Jian, Yang Lin

机构信息

Department of Rehabilitation Medicine, West China Hospital Affiliated to Sichuan University, Chengdu, Sichuan 610041, China.

出版信息

Chin Med J (Engl). 2008 Oct 20;121(20):2095-9.

PMID:19080282
Abstract

OBJECTIVE

To understand the effects of low-frequency pulsed electromagnetic fields (PEMFs) on chronic bony pain, bone mineral density (BMD), bone strength and biochemical markers of bone metabolism in the patients of osteoporosis.

DATA SOURCES

Using the key words "pulsed electromagnetic fields" and "osteoporosis", we searched the PubMed for related studies published in English from January 1996 to December 2007. We also searched the China National Knowledge Infrastructure (CNKI) for studies published in Chinese from January 1996 to December 2007.

INCLUSION CRITERIA

(1) all articles which referred to the effects of low-frequency pulsed magnetic fields on osteoporosis either in primary osteoporosis or secondary osteoporosis; (2) either observational studies or randomized controlled studies.

EXCLUSION CRITERIA

(1) articles on experimental studies about osteoporosis; (2) repetitive studies; (3) case reports; (4) meta analysis.

RESULTS

Totally 111 related articles were collected, 101 of them were published in Chinese, 10 were in English. Thirty-four were included and the remaining 84 were excluded.

CONCLUSIONS

Low-frequency PEMFs relieves the pain of primary osteoporosis quickly and efficiently, enhances bone formation and increases BMD of secondary osteoporosis. But the effects of PEMFs on bone mineral density of primary osteoporosis and bone resorption were controversial.

摘要

目的

了解低频脉冲电磁场(PEMFs)对骨质疏松症患者慢性骨痛、骨密度(BMD)、骨强度及骨代谢生化标志物的影响。

资料来源

采用“脉冲电磁场”和“骨质疏松症”作为关键词,检索1996年1月至2007年12月期间发表在英文期刊上的相关研究,检索数据库为PubMed。同时检索中国知网(CNKI),获取1996年1月至2007年12月期间发表的中文相关研究。

纳入标准

(1)所有提及低频脉冲磁场对原发性骨质疏松症或继发性骨质疏松症影响的文章;(2)观察性研究或随机对照研究。

排除标准

(1)关于骨质疏松症的实验性研究文章;(2)重复性研究;(3)病例报告;(4)荟萃分析。

结果

共收集到111篇相关文章,其中101篇为中文,10篇为英文。纳入34篇,排除其余84篇。

结论

低频脉冲电磁场能快速有效地缓解原发性骨质疏松症的疼痛,促进继发性骨质疏松症的骨形成并增加骨密度。但脉冲电磁场对原发性骨质疏松症骨密度及骨吸收的影响存在争议。

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