Vlaski E, Stavric K, Seckova L, Kimovska M, Isjanovska R
Department of Pulmonology and Allergology. University Children's Hospital. Skopje. The Republic of Macedonia.
Allergol Immunopathol (Madr). 2008 Sep-Oct;36(5):247-53. doi: 10.1016/s0301-0546(08)75218-2.
Related to exercise hypothesis, the aim of the present study was to explore the influence of physical activity on asthma and allergic rhinitis in a developing country where publicity campaigns about the benefits of exercise are scarce.
The analysed data were self-reported and obtained through the standardized International Study of Asthma and Allergies in Childhood Phase Three written questionnaires completed by 3026 adolescents 13/14 year old in Skopje (Republic of Macedonia). Vigorous physical activity and television-watching timeboth unadjusted and adjusted for confounding factorswere used as variables for analysis. Odds ratios (OR, 95 % CI) in binary logistic regression were employed for statistic analysis of the data.
Vigorous physical activity both > or = 3 times and 1-2 times per week was associated with an increased risk of current wheeze (aOR: 1.66; 1.08-2.55; p = 0.020 and aOR: 1.70; 1.23-2.36; p = 0.001, respectively), speech-limiting wheeze (aOR: 3.15; 1.13-8.77; p = 0.028 and aOR: 4.62; 2.22-9.62; p = 0.000, respectively) and exercise-induced wheeze (aOR: 2.72; 1.93-3.83; p = 0.000 and aOR: 4.01; 3.12-5.14; p = 0.000, respectively). Frequent physical activity was positively associated only with current allergic rhinitis symptoms (aOR: 1.40; 1.04-1.90; p = 0.029). Television watching > or = 3 hours a day increased the risk of current wheeze (aOR: 1.34; 1.01-1.77; p = 0.042) and exercise-induced wheeze (aOR: 1.32; 1.05-1.65; p = 0.016).
The findings support the aggravating role of sedentary regimen and poor physical fitness on asthma symptoms, but not on allergic rhinitis. Physical activity may trigger asthma symptoms when physical fitness is poor and asthma is not controlled.
与运动假说相关，本研究旨在探讨身体活动对一个缺乏运动益处宣传活动的发展中国家的哮喘和过敏性鼻炎的影响。
分析的数据为自我报告数据，通过斯科普里（马其顿共和国）3026名13/14岁青少年完成的标准化儿童哮喘和过敏国际研究第三阶段书面问卷获得。剧烈身体活动和看电视时间（未调整和调整混杂因素后）用作分析变量。二元逻辑回归中的比值比（OR，95%可信区间）用于数据的统计分析。
每周剧烈身体活动≥3次和1 - 2次均与当前喘息风险增加相关（调整后比值比分别为：1.66；1.08 - 2.55；p = 0.020和1.70；1.23 - 2.36；p = 0.001）、言语受限性喘息（调整后比值比分别为：3.15；1.13 - 8.77；p = 0.028和4.62；2.22 - 9.62；p = 0.000）和运动诱发的喘息（调整后比值比分别为：2.72；1.93 - 3.83；p = 0.000和4.01；3.12 - 5.14；p = 0.000）。频繁的身体活动仅与当前过敏性鼻炎症状呈正相关（调整后比值比为：1.40；1.04 - 1.90；p = 0.029）。每天看电视≥3小时会增加当前喘息风险（调整后比值比为：1.34；1.01 - 1.77；p = 0.042）和运动诱发的喘息风险（调整后比值比为：1.32；1.05 - 1.65；p = 0.016）。
研究结果支持久坐不动的生活方式和身体素质差对哮喘症状有加重作用，但对过敏性鼻炎没有。当身体素质差且哮喘未得到控制时，身体活动可能会引发哮喘症状。
