Guiote-Domínguez M V, Muñoz-Hoyos A, Gutiérrez-Salmerón M T
Servicio de Dermatología, Hospital Clínico Universitario San Cecilio, Granada, España.
Actas Dermosifiliogr. 2008 Oct;99(8):628-38.
Atopic dermatitis is a common and increasingly prevalent disorder. The International Study of Asthma and Allergies in Childhood (ISAAC) made a major contribution to the understanding of its epidemiology.
The aim of this study was to estimate the prevalence and severity of atopic dermatitis in a representative sample of 6 to 7-year-old and 13 to 14-year-old children from the province of Granada, Spain, using validated questionnaires and to analyze potential differences between coastal and inland regions.
This was a descriptive cross-sectional observational study of schoolchildren from Granada, Spain, aged between 6 and 7 years and 13 and 14 years. The main instrument was the core questionnaire module for dermatitis used in phase I of the ISAAC study.
Statistically significant differences were found in Granada schoolchildren aged 6 to 7 years in terms of prevalence of dermatitis at some time, typical site, resolution in the last 12 months, and diagnosis of atopic dermatis. No significant differences were observed on comparison of the prevalence of atopic dermatitis between coastal and inland populations. Finally, in the comparison of schoolchildren aged 6 to 7 years, we observed almost significant differences for dermatitis at some time, resolution in the last 12 months, and diagnosis of atopic dermatitis on considering age and geographic location of the study population.
The prevalence of atopic dermatitis is similar in the coastal population and the provincial capital. In terms of clinical symptoms and disease course, atopic dermatitis tends to stabilize with age.
特应性皮炎是一种常见且日益普遍的疾病。儿童哮喘和过敏国际研究（ISAAC）对其流行病学的理解做出了重大贡献。
本研究旨在使用经过验证的问卷，估计西班牙格拉纳达省6至7岁和13至14岁儿童代表性样本中特应性皮炎的患病率和严重程度，并分析沿海和内陆地区之间的潜在差异。
这是一项对西班牙格拉纳达6至7岁和13至14岁学童的描述性横断面观察研究。主要工具是ISAAC研究第一阶段使用的皮炎核心问卷模块。
在格拉纳达6至7岁的学童中，在某些时候的皮炎患病率、典型部位、过去12个月内的缓解情况以及特应性皮炎的诊断方面发现了统计学上的显著差异。沿海和内陆人群特应性皮炎患病率比较未观察到显著差异。最后，在6至7岁学童的比较中，考虑研究人群的年龄和地理位置，我们在某些时候的皮炎、过去12个月内的缓解情况以及特应性皮炎的诊断方面观察到了几乎显著的差异。
沿海人群和省会城市特应性皮炎的患病率相似。在临床症状和病程方面，特应性皮炎倾向于随年龄稳定。
