Stewart M P
Cottage Hospital, Anguilla, British West Indies.
Trop Doct. 1991 Apr;21(2):54-5. doi: 10.1177/004947559102100204.
Intravenous mannitol was given to 16 patients with acute ciguatera fish poisoning requiring hospital admission. Thirteen patients (81%) presented with sensory and neuromuscular symptoms; paraesthesiae and pain and weakness in the lower limbs were predominant features. Mannitol had little effect upon gastrointestinal manifestations, but a marked reduction was observed in the expected duration of neurological symptoms. Although these results are empirical and uncontrolled, they suggest that mannitol infusion may be effective in altering the clinical course of acute ciguatera fish poisoning.
16例因急性雪卡鱼中毒需住院治疗的患者接受了静脉注射甘露醇。13例患者（81%）出现感觉和神经肌肉症状；主要表现为感觉异常、疼痛以及下肢无力。甘露醇对胃肠道症状影响不大，但观察到神经症状的预期持续时间显著缩短。尽管这些结果是基于经验且未设对照的，但它们表明静脉输注甘露醇可能有效改变急性雪卡鱼中毒的临床病程。
