聚糖生物标志物在疾病诊断中的前景。
The prospects of glycan biomarkers for the diagnosis of diseases.
作者信息
Lebrilla Carlito B, An Hyun Joo
机构信息
Department of Chemistry, University of California, Davis, USA.
出版信息
Mol Biosyst. 2009 Jan;5(1):17-20. doi: 10.1039/b811781k. Epub 2008 Nov 6.
DOI:10.1039/b811781k
PMID:19081926
Abstract
Over 40 years of literature shows that glycosylation is greatly affected by diseases such as cancer. This opinion article argues the intrinsic advantages of using glycans as disease markers over other biomolecules and the potential of glycan profiling for diagnosing and determining the progression of disease.
摘要
40多年的文献表明，糖基化会受到诸如癌症等疾病的极大影响。这篇观点文章论证了相较于其他生物分子，使用聚糖作为疾病标志物的内在优势，以及聚糖分析在疾病诊断和病情进展判定方面的潜力。
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