Tanemura H, Azuma S, Saji S, Kawata R, Furuta T, Miya K, Umemoto T, Kunieda K, Takao H, Sugiyama Y
Second Dept. of Surgery, Gifu University School of Medicine, Japan.
Gan To Kagaku Ryoho. 1991 Aug;18(10):1695-8.
A 55-year-old woman with gastric cancer underwent laparotomy and was found to have an unresectable tumor characterized by S3 (invasion of the pancreas), N3, P0 and H0. She was then treated by combined administration of cisplatinum, mitomycin C and 5-fluorouracil. A remarkable response (CR) was confirmed by upper gastrointestinal roentgenography and endoscopy. Upon reoperation about 8 weeks after chemotherapy, a successful radical total gastrectomy with R2 (partially R3) lymphnode dissection was performed. Histological examination of the specimens, including the stomach and lymphnodes, revealed no cancer cells in any region (pCR). She had been given UFT and PSK for 4 years 4 months after reoperation. She has lived for 5 years 2 months after reoperation without any signs of recurrence or metastases.
一名55岁的胃癌女性接受了剖腹手术，发现有一个无法切除的肿瘤，特征为S3（侵犯胰腺）、N3、P0和H0。随后她接受了顺铂、丝裂霉素C和5-氟尿嘧啶的联合给药治疗。上消化道X线造影和内镜检查证实有显著反应（CR）。化疗约8周后再次手术，成功进行了R2（部分为R3）淋巴结清扫的根治性全胃切除术。对包括胃和淋巴结在内的标本进行组织学检查，发现任何区域均无癌细胞（pCR）。再次手术后她接受了4年4个月的优福定和云芝多糖K治疗。再次手术后她已存活5年2个月，无任何复发或转移迹象。
