Nakagawa K, Kitani E, Takashima Y, Yamamichi N, Tsuda S, Yamazaki S
Dept. of Surgery, Fukui Prefectural Hospital.
Gan To Kagaku Ryoho. 1990 Aug;17(8 Pt 2):1804-7.
A 64-year-old woman with Borrmann type 4 gastric cancer was treated by intraaortic (celiac artery) one-shot infusion chemotherapy with adriamycin (ADM) and mitomycin C (MMC). One month after the first administration of 30 mg ADM and 20 mg MMC, the second administration of 50 mg ADM and 20 mg MMC was done. The third administration of 50 mg ADM and 20 mg MMC was performed one month after the second administration. Clinical symptoms of back pain, lumbago and anorexia had almost disappeared soon after the third administration. Although the findings of the X-ray examination of stomach, gastroscopy and celiac angiography showed marked improvement, total gastrectomy with lymphadenectomy was performed 2 months after the third administration because residual cancer cell nests were highly suspect. Histological examination of the resected stomach and lymphnodes revealed no cancer cells. The patient has been in good health without any recurrent signs for 16 months after operation.
一名64岁的Borrmann 4型胃癌女性患者接受了腹腔动脉一次性主动脉内灌注阿霉素（ADM）和丝裂霉素C（MMC）化疗。首次给予30mg ADM和20mg MMC一个月后，进行了第二次给药，给予50mg ADM和20mg MMC。第二次给药一个月后进行了第三次给药，给予50mg ADM和20mg MMC。第三次给药后不久，背痛、腰痛和厌食等临床症状几乎消失。尽管胃部X线检查、胃镜检查和腹腔血管造影结果显示有明显改善，但由于高度怀疑有残留癌细胞巢，在第三次给药2个月后进行了全胃切除术及淋巴结清扫术。切除的胃和淋巴结的组织学检查未发现癌细胞。患者术后16个月一直健康，无任何复发迹象。
