Atalar Ebru, Aydin Gülümser, Keles Isik, Inal Elem, Zog Gulfer, Arslan Ayse, Orkun Sevim
Department of Physical Medicine and Rehabilitation, Ataturk Training and Research Hospital for Chest Diseases and Thoracic Surgery, Ankara, Turkey.
Rheumatol Int. 2009 Jul;29(9):1025-30. doi: 10.1007/s00296-008-0768-4. Epub 2008 Dec 10.
In this study, in 131 men aged 20-75 years, we investigated correlations between bone mineral density (BMD) in the lumbar spine and femoral neck and endogenous factors (age, body mass index) as well as exogenous factors (calcium intake, physical activity, smoking, caffeine, socioeconomic and educational levels). The age had a negative effect on femoral neck BMD in patients overall, and on both lumbar spine and femoral neck BMD in patients under 50. Physical activity has effects on femoral neck BMD in men above 50. Lumbar vertebral BMD negatively correlated with smoking in patients overall, and this correlation persisted when patients aged 50 and older were analyzed separately. Femoral neck BMD was positively correlated with body mass index in men aged 50 and older. Given the variety of findings in the research literature regarding risk factors for low BMD, we suggest that genetic and geographic factors should be considered.
在本研究中，我们对131名年龄在20至75岁之间的男性进行了调查，研究腰椎和股骨颈骨矿物质密度（BMD）与内源性因素（年龄、体重指数）以及外源性因素（钙摄入量、身体活动、吸烟、咖啡因、社会经济和教育水平）之间的相关性。年龄对总体患者的股骨颈骨密度有负面影响，对50岁以下患者的腰椎和股骨颈骨密度均有负面影响。身体活动对50岁以上男性的股骨颈骨密度有影响。总体患者中，腰椎骨密度与吸烟呈负相关，在单独分析50岁及以上患者时，这种相关性依然存在。50岁及以上男性的股骨颈骨密度与体重指数呈正相关。鉴于研究文献中关于低骨密度风险因素的各种发现，我们建议应考虑遗传和地理因素。
