Gombos Tímea, Kertész Krisztina, Csíkos Agnes, Söderhamn Ulrika, Söderhamn Olle, Prohászka Zoltán
IIIrd Department of Internal Medicine, Faculty of Medicine, Semmelweis University, 1125 Budapest, Hungary.
Nutr Res. 2008 Feb;28(2):59-65. doi: 10.1016/j.nutres.2007.12.003.
Undernutrition is a common problem associated with clinical complications such as impaired immune response, reduced muscle strength, impaired wound healing, and susceptibility to infections; therefore, it is an important treatment target to reduce morbidity and mortality associated with chronic diseases and aging. The aim of the present study was to apply a reliable and valid instrument for the determination of undernutrition risk in an in-hospital patient population and to describe possible associations between risk of undernutrition and some aspects of health-related quality of life in patients with chronic diseases. Fifty-six adult patients with different chronic diseases were interviewed with NUFFE questionnaire and the EQ-5D. Anthropometric measurements were performed. Reliability and validity of the NUFFE instrument was tested, and its correlation with EQ-5D was calculated. Euro-Qol scores correlated significantly with the total NUFFE scores and with the items constructing the most important factor of the instrument, explaining 53.74% of its variance. Nutritional form for the elderly was shown to be a reliable instrument in the study group because its internal consistency measured by Cronbach alpha was 0.62, and the item-total score correlations were significant for the half of the items. Criterion-related validity, concurrent validity, and construct validity of NUFFE were established. We have shown that impaired level of health-related quality of life is an important determinant of risk for undernutrition. Nutritional form for the elderly is an appropriate instrument to estimate undernutrition risk in a general, in-hospital patient population with various chronic diseases and to identify "at risk" patients who may benefit from professional dietary interventions to reduce undernutrition-related complications.
营养不良是一个常见问题,与免疫反应受损、肌肉力量减弱、伤口愈合不良和易感染等临床并发症相关;因此,它是降低与慢性病和衰老相关的发病率和死亡率的重要治疗靶点。本研究的目的是应用一种可靠且有效的工具来确定住院患者群体中的营养不良风险,并描述慢性病患者营养不良风险与健康相关生活质量某些方面之间可能存在的关联。对56名患有不同慢性病的成年患者进行了NUFFE问卷和EQ-5D访谈。进行了人体测量。测试了NUFFE工具的信度和效度,并计算了其与EQ-5D的相关性。欧洲五维度健康量表(Euro-Qol)得分与NUFFE总分以及构成该工具最重要因素的项目显著相关,解释了其53.74%的方差。在研究组中,老年营养量表被证明是一种可靠的工具,因为其通过克朗巴赫α系数测量的内部一致性为0.62,且一半项目的项目总分相关性显著。建立了NUFFE的标准关联效度、同时效度和结构效度。我们已经表明,健康相关生活质量受损是营养不良风险的一个重要决定因素。老年营养量表是评估一般住院慢性病患者群体中营养不良风险以及识别可能从专业饮食干预中受益以减少与营养不良相关并发症的“风险”患者的合适工具。