Suppr超能文献

芬兰境内Y染色体的高度差异——法医学方面

High degree of Y-chromosomal divergence within Finland--forensic aspects.

作者信息

Palo Jukka U, Hedman Minttu, Ulmanen Ismo, Lukka Matti, Sajantila Antti

机构信息

Department of Forensic Medicine, P.O. Box 40, University of Helsinki, FIN-00014 Helsinki, Finland.

出版信息

Forensic Sci Int Genet. 2007 Jun;1(2):120-4. doi: 10.1016/j.fsigen.2007.02.001. Epub 2007 Mar 9.

Abstract

Among the Finns, the levels of autosomal STR and mtDNA variation have been reported to be relatively high and evenly distributed throughout the country. In contrast, the Y-STR variation is markedly lower than observed in most other European populations, showing notable geographical substructure within Finland. There are striking interregional differences--the western, middle and eastern parts of Finland segregate clearly, with phiST values comparable to the highest divergences among European populations. The low Y-STR diversity reduces the discriminative power of Y-chromosomal markers among Finns, and, furthermore, the geographical substructure complicates the assessment of profile probabilities in forensic settings. Here, the Y-STR diversity pattern in Finland is for the first time evaluated from the forensic viewpoint.

摘要

据报道,在芬兰人中,常染色体短串联重复序列(autosomal STR)和线粒体DNA(mtDNA)的变异水平相对较高,且在全国分布均匀。相比之下,Y染色体短串联重复序列(Y-STR)的变异明显低于大多数其他欧洲人群,在芬兰境内呈现出显著的地理亚结构。地区间存在显著差异——芬兰的西部、中部和东部明显分开,PhiST值与欧洲人群中最高的差异相当。Y-STR多样性较低降低了Y染色体标记在芬兰人中的鉴别能力,此外,地理亚结构使法医环境中轮廓概率的评估变得复杂。在此,首次从法医角度评估了芬兰的Y-STR多样性模式。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验