Rubinow Marisa J, Hagerbaumer Diana A, Juraska Janice M
Department of Psychology, University of Illinois, Champaign, IL 61820, USA.
Behav Brain Res. 2009 Mar 2;198(1):263-6. doi: 10.1016/j.bbr.2008.11.024. Epub 2008 Nov 24.
The rat basolateral amygdala shows neuroanatomical sex differences, continuing development after puberty and aging-related alterations. Implications for amygdala-dependent memory processes were explored here by testing male and female hooded rats in adolescence, adulthood and old age on the food-conditioned place preference task. While aged rats were unimpaired, adolescents failed to learn the task. This finding may be related to ongoing development of the basolateral amygdala and related memory systems during the adolescent period.
大鼠基底外侧杏仁核表现出神经解剖学上的性别差异，青春期后持续发育以及与衰老相关的改变。本文通过在食物条件性位置偏好任务中测试青春期、成年期和老年期的雄性和雌性戴帽大鼠，探讨了杏仁核依赖性记忆过程的影响。虽然老年大鼠未受损，但青春期大鼠未能学会该任务。这一发现可能与青春期基底外侧杏仁核及相关记忆系统的持续发育有关。
