Tschoppe Peter, Neumann Konrad, Mueller Jan, Kielbassa Andrej M
Department of Operative Dentistry and Periodontology, University School of Dental Medicine, CharitéCentrum 3, Germany.
J Dent. 2009 Feb;37(2):156-62. doi: 10.1016/j.jdent.2008.11.001. Epub 2008 Dec 11.
This study evaluated possible differences regarding the remineralization of predemineralized enamel after exposure to fluoridated or non-fluoridated bleaching gels.
120 enamel specimens were prepared from sixty bovine incisors; before and after demineralization (37 degrees C; pH 4.95; 10d), one-quarter of each specimen's surface was covered with nail varnish (control sound/demineralized). Subsequently, the specimens were stored for 16h daily in a remineralizing solution (pH 7.0; 14d), while for the remaining time (8h) various bleaching gels were applied: (1) no treatment (control), (2) Opalescence regular (O, Ultradent), (3) Opalescence PF (O-PF), (4) Nite White ACP (NW-ACP, Discus Dental) and (5) Nite White ACPF (NW-ACPF). Following, half of the bleached parts were nail-varnished and stored for another 3-weeks period in a remineralizing solution. Differences in mineral losses (DeltaDeltaZ) and lesion depths (DeltaLD) before and after treatment/remineralization period were evaluated from microradiographs. DeltaDeltaZ(surface) values (mineral loss of the outer 18microm of the lesion) were calculated.
After 2 and 5 weeks DeltaDeltaZ/DeltaLD values of the bleaching groups did not differ significantly from the controls. Treatment with NW-ACPF for 2 weeks resulted in significantly lower DeltaDeltaZ values compared to NW-ACP (p=0.032) and NW-ACPF in higher values than Opalescence regular (p=0.006). Two weeks treatment with O and O-PF resulted in decreased DeltaDeltaZ(surface) values compared to control (p<0.0005), whereas with NW-ACPF no significant differences could be observed (p=0.062). Application of NW-ACP induced significantly increased DeltaDeltaZ(surface) values compared to control (p=0.001).
No supporting influence of fluoride-containing bleaching gels on remineralization could be observed.
本研究评估了预脱矿牙釉质在接触含氟或不含氟漂白凝胶后再矿化方面可能存在的差异。
从60颗牛切牙制备120个牙釉质标本；在脱矿（37℃；pH 4.95；10天）前后，每个标本表面的四分之一用指甲油覆盖（对照完好/脱矿）。随后，标本每天在再矿化溶液（pH 7.0；14天）中保存16小时，其余时间（8小时）应用各种漂白凝胶：（1）不处理（对照），（2）皓齿常规型（O，Ultradent），（3）皓齿PF型（O-PF），（4）夜间美白含ACP（NW-ACP，Discus Dental）和（5）夜间美白含ACPF（NW-ACPF）。之后，将一半漂白部分用指甲油覆盖，并在再矿化溶液中再保存3周。从显微放射照片评估治疗/再矿化期前后矿物质损失（ΔΔZ）和病变深度（ΔLD）的差异。计算ΔΔZ（表面）值（病变外层18微米的矿物质损失）。
2周和5周后，漂白组的ΔΔZ/ΔLD值与对照组无显著差异。与NW-ACP相比，用NW-ACPF治疗2周导致ΔΔZ值显著降低（p = 0.032）；与皓齿常规型相比NW-ACPF值更高（p = 0.006）。与对照相比，用O和O-PF治疗2周导致ΔΔZ（表面）值降低（p <0.0005），而用NW-ACPF未观察到显著差异（p = 0.062）；与对照相比NW-ACP的应用导致ΔΔZ（表面）值显著增加（p = 0.001）。
未观察到含氟漂白凝胶对再矿化有支持作用。
